2026-05-16T07:42:41Z https://journal-ijcnp.com/index.php/IJCNP/oai

oai:ojs2.journal-ijcnp.com:article/4 2022-12-02T15:56:07Z IJCNP:RA

POTENSI NIGELLA SATIVA DALAM PENGOBATAN COVID-19 Yuniarti, Heny Fasitasari, Minidian Wibowo, Joko Wahyu COVID-19 membutuhkan berbagai intervensi untuk menekan angka kesakitan dan kematiannya. Tujuan penelitian ini adalah  mencari terapi adjuvan yang dapat meringankan gejala dan   mengurangi angka kematian yang diakibatkan oleh COVID-19. Referensi yang membahas mengenai  manfaat Nigella Sativa  seperti dari Biomed Central, Elsevier,  Journal of Pharmacopuncture dan berbagai referensi lain dikumpulkan untuk mencari  peran Nigella Sativa. Manfaat Nigella Sativa disusun sebagai terapi adjuvan dari berbagai  penelitian seperti penelitian in vitro, Randomized Control Trial, maupun  clinical trial. Kata kunci pencarian yang digunakan seperti  Nigella Sativa, Black Seed, dan Covid-19.  Hasil  penelitian membuktikan konstituen bioaktif dari Nigella Sativa seperti thymoquinone (TQ),   trans-anethol,  nigellidine , nigellicine, nigellicimine-N-oksida dan α-hederin1 memiliki beragam manfaat  seperti anti oksidan, anti inflamasi, immunomodulator, antitusif, antihipertensi dan menyeimbangkan kadar gula darah. Kesimpulan yang didapatkan bahwa Nigella Sativa dapat dipertimbangkan sebagai terapi adjuvan untuk mengurangi angka kesakitan dan  kematian  akibat COVID-19. Perhimpunan Dokter Gizi Klinik Indonesia 2020-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/4 10.54773/ijcnp.v3i1.4 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 3 No. 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 89-102 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 3 No 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 89-102 2775-5215 2597-4297 10.54773/ijcnp.v3i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/4/54

oai:ojs2.journal-ijcnp.com:article/13 2022-12-02T15:56:07Z IJCNP:CR

TERAPI NUTRISI PADA STROKE PERDARAHAN DISERTAI HIPONATREMIA DAN HIPOKALEMIA Lista Andriyati Suryani As’ad Nurbaya Syam Aryanty R Bamahry Stroke adalah episode disfungsi neurologis akut yang diduga disebabkan oleh iskemia atau perdarahan, bertahan setidaknya 24 jam atau sampai kematian, tetapi tanpa bukti yang cukup untuk diklasifikasikan selain vaskular. Stroke perdarahan menyebabkan kecacatan dan kematian yang signifikan. Dengan perawatan yang optimal sekalipun, lebih dari 30% pasien stroke mengalami cacat berat pasca stroke. Malnutrisi seringkali ditemukan pada pasien stroke akut dan selama periode rehabilitasi. Malnutrisi  berhubungan erat dengan luaran yang buruk pada pasien. Pada laporan kasus ini didapatkan seorang laki-laki usia 64 tahun dengan keluhan tidak dapat makan dan minum melalui mulut karena kesadaran menurun dan didiagnosis perdarahan otak non traumatik dengan moderate protein energy malnutrition, leukositosis (11.700 103/uL), deplesi sedang system imun (1029,6 cell/m3), hiponatremia sedang (126 mmol/L), hipokalemia ringan (3,2 mmol/L).  Terapi  nutrisi diberikan  2100 kkal energi, protein 1,5 g/ kgBBI/hari, karbohidrat 287,5 g dan lemak 85,6 g berupa nutrisi enteral. Suplementasi diberikan zinc, b kompleks, curcuma, asam folat dan ksr. Setelah 15 hari perawatan, pasien mengalami perbaikan klinis dan metabolik. Pentingnya penilaian awal dan terapi dini sangat diperlukan guna mencegah terjadinya malnutrisi dan menghasilkan luaran yang baik. Perhimpunan Dokter Gizi Klinik Indonesia 2020-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/13 10.54773/ijcnp.v3i1.13 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 3 No. 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 1-9 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 3 No 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 1-9 2775-5215 2597-4297 10.54773/ijcnp.v3i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/13/31

oai:ojs2.journal-ijcnp.com:article/14 2022-12-02T15:56:06Z IJCNP:CR

TERAPI GIZI PADA ADENOCARSINOMA ESOPHAGEAL JUNCTION POST GASTRECTOMI PARTIAL DAN GASTROSTOMI FEEDING Nur Husain, Fatmawati Bukhari, Agussalim Safitri, Asrini Syam, Nurbaya Intervensi nutrisi harus menjadi bagian penting dari pendekatan multimoda terhadap kanker kaheksia. Tujuan utama terapi nutrisi pada penderita kanker adalah mempertahankan atau meningkatkan status gizi sehingga dapat memperkecil terjadinya komplikasi, meningkatkan efektivitas terapi kanker (bedah, kemoterapi, radiasi), kualitas hidup dan survival penderita. Pria usia 60 tahun dikonsulkan dengan diagnosis Gastroesophageal junction adenocarcionma (GEJAC) dan malnutrisi berat (Subjective Global Assesment Skor C). Pasien memiliki riwayat asupan yang kurang dan perubahan konsistensi asupan selama 6 bulan dan memberat 1 bulan terakhir karena disfagia. Terapi nutrisi pre-operatif diberikan dengan target 2100 kkal secara bertahap melalui oral dan parenteral dengan protein 1,5 gram/kgBB ideal/hari. Pemberian nutrisi post-operasi dimulai bertahap melalui enteral (gastrostomi) dan parenteral dengan protein dinaikkan menjadi 1,7 gram/kgBB ideal/hari. Pada akhir masa perawatan terdapat perbaikan metabolik seperti albumin dan jumlah leukosit dari post-operasi hingga akhir masa perawatan. Penganan nutrisi perlu dilakukan pada pasien kanker yang akan menjalani operasi untuk optimalisasi kondisi pre-operasi dan memperbaiki klinis dan metabolik pasien post-operasi. Perhimpunan Dokter Gizi Klinik Indonesia 2020-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/14 10.54773/ijcnp.v3i1.14 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 3 No. 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 10-18 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 3 No 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 10-18 2775-5215 2597-4297 10.54773/ijcnp.v3i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/14/32

oai:ojs2.journal-ijcnp.com:article/18 2022-12-02T15:56:06Z IJCNP:CR

PENGARUH TERAPI NUTRISI PADA PASIEN POST OPERASI LAPARATOMI EKSPLORASI THREE OSTOMY DECOMPRESSION, JEJUNOSTOMY FEEDING, PERFORASI GASTER, LASERASI DUODENUM PARS IV ET CAUSA TRAUMA TUMPUL ABDOMEN, FISTEL ENTEROKUTAN DAN HIPOALBUMINEMIA Thewakan, Josephine Bukhari, Agussalim Syam, Nurbaya Ashari, Nur Pendahuluan: Trauma merupakan salah satu penyebab utama kematian di negara maju dan berkembang. Meningkatnya metabolisme pada trauma, menyebabkan pemecahan massa tubuh tanpa lemak, yang dapat berkontribusi pada terjadinya malnutrisi, sehingga diperlukan terapi nutrisi yang adekuat. Laporan Kasus: Kami laporkan laki-laki, berusia 19 tahun dikonsul dari bagian bedah digestif, dengan asupan via parenteral dialami sejak 5 hari lalu karena dipuasakan post operasi. Riwayat demam dan muntah 6 hari lalu. Ada batuk dan sesak. Pemeriksaan fisik didapatkan kesadaran compos mentis, tanda vital dalam batas normal, terpasang NGT dekompresi, O2 via nasal kanul, drain cavum douglasi, gastrostomi dekompresi, serta jejunostomy feeding. Hari ke 10 post operasi ditemukan fistel enterokutan pada luka operasi. Hasil laboratorium didapatkan anemia, leukositosis, hipertrigliserida, hipoalbuminemia, deplesi berat sistem imun serta ketidakseimbangan elektrolit. Status gizi moderate protein energy malnutrition. Terapi nutrisi diberikan secara bertahap sesuai toleransi dengan target 2400 kkal dan protein 1,7-2 gr/kgBBI/hari via parenteral. Pada hari ke 28 perawatan mulai diberikan via oral dan parenteral untuk mencukupi kebutuhan. Selain itu, diberikan suplementasi Cernevit 1 ampul/24 jam/IV dan neurobion 1 ampul/24 jam/IM. Setelah 60 hari perawatan, pasien dapat makan sepenuhnya via oral dan luka fistel menutup. Kesimpulan: Terapi nutrisi yang tepat penting untuk meningkatkan hasil akhir pada pasien. Perhimpunan Dokter Gizi Klinik Indonesia 2020-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/18 10.54773/ijcnp.v3i1.18 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 3 No. 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 29-37 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 3 No 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 29-37 2775-5215 2597-4297 10.54773/ijcnp.v3i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/18/34

oai:ojs2.journal-ijcnp.com:article/20 2022-12-02T15:56:05Z IJCNP:RA

HUBUNGAN DERAJAT KEPARAHAN STROKE DENGAN PERUBAHAN STATUS GIZI PASIEN DI UNIT STROKE Camelia Bomaztika Sari Hertanto Wahyu Subagio Etisa Adi Murbawani Latar belakang : Defisit neurologis akibat stroke akut menyebabkan perburukan malnutrisi selama perawatan di rumah sakit dan dikaitkan dengan outcome klinis lebih buruk, masa rawat lebih lama dan biaya lebih besar. Tujuan: Menganalisis hubungan derajat keparahan stroke dengan perubahan status gizi pasien selama pelayanan di Unit Stroke dan faktor-faktor yang mempengaruhinya. Metode : Penelitian cross-sectional dilakukan di Unit Stroke RSUP dr. Kariadi Semarang pada bulan Maret - Mei 2019 terhadap 60 subyek pasien stroke yang dipilih secara consecutive sampling serta memenuhi kriteria inklusi dan eksklusi. Penilaian NIHSS dilakukan pada awal dan akhir pengamatan; pengukuran dan perubahan LLA pada hari ke-1, ke-3, ke-7, ke-14; status diare serta status disfagia. Uji Chi-square dilakukan untuk melihat hubungan antara derajat keparahan stroke dengan faktor-faktor yang berhubungan dengan perubahan status gizi pasien. Hasil: Derajat keparahan stroke sedang dan berat lebih banyak dijumpai. Target pemenuhan energi hari ke-5 dapat dicapai 80% subyek, penurunan LLA 35%, diare 11,7% dan disfagia 46,7%. Terdapat hubungan signifikan antara derajat keparahan stroke dengan perubahan LLA (p < 0,05). Simpulan : Derajat keparahan stroke berhubungan dengan perubahan status gizi selama perawatan yang dinilai dari penurunan LLA. Perhimpunan Dokter Gizi Klinik Indonesia 2020-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/20 10.54773/ijcnp.v3i1.20 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 3 No. 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 65-79 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 3 No 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 65-79 2775-5215 2597-4297 10.54773/ijcnp.v3i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/20/38

oai:ojs2.journal-ijcnp.com:article/21 2022-12-02T15:56:05Z IJCNP:CR

TERAPI NUTRISI PADA PASIEN CARDIAC CACHEXIA ET CAUSA CHRONIC HEART FAILURE NYHA III DENGAN PENYULIT EDEMA PARU KARDIOGENIK AKUT Layle Rahmiyanti Suryani As’ad Nurbaya Syam Pendahuluan Cardiac cachexia (CC) adalah penurunan berat badan dengan/ tanpa muscle wasting pada pasien gagal jantung. Terapi nutrisi merupakan salah satu upaya untuk mencegah perburukan klinis CC. Laporan Kasus Ny.R, 54 tahun dikonsultasikan dengan diagnosa edema paru kardiogenik akut dan congestive heart failure NYHA III. Keluhan utama berupa masukan makan berkurang sejak 1 tahun dan memberat dalam 8 hari terakhir karena sesak  napas. Ada riwayat penurunan berat badan, namun tidak diketahui besar penurunannya. Tampak lemah dan sesak napas. Antropometri: TB 154 cm, LLA 19.5 cm. Terdapat kehilangan jaringan lemak subkutan dan muscle wasting tanpa edema. Handgrip strength 5.2 kg. Food recall 24 hour 343 kkal. Status gizi buruk berdasarkan SGA. Terapi nutrisi: kalori 1600 kkal diberikan bertahap, dengan komposisi makronutrien: karbohidrat 45-50%, protein 1.5 gr/kgBBI/hari dan lemak 32-37%. Diberikan nutrient spesifik berupa EPA dan BCAA. Suplementasi mikronutrien: zink, curcuma, vitamin Bkompleks, thiamin dan ekstrak ikan gabus. Setelah Pasien dipulangkan, kami lakukan pemantauan selama 8 bulan untuk menilai asupan kalori, berat badan dan kapasitas fungsional serta kepatuhan pasien terhadap program terapi nutrisi yang diberikan. Terdapat perbaikan klinis peningkatan asupan energi, berat badan yang stabil, dan peningkatan kapasitas fungsional. Kesimpulan Terapi nutrisi yang adekuat dan pemberian nutrient spesifik dapat mencegah perburukan CC. Perhimpunan Dokter Gizi Klinik Indonesia 2020-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/21 10.54773/ijcnp.v3i1.21 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 3 No. 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 38-45 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 3 No 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 38-45 2775-5215 2597-4297 10.54773/ijcnp.v3i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/21/35

oai:ojs2.journal-ijcnp.com:article/22 2022-12-02T15:56:04Z IJCNP:CR

PERANAN ZINK DAN VITAMIN D TERHADAP PENCEGAHAN TERJADINYA IMMUNE RECONSTITUTION INFLAMATORY SYNDROME (IRIS) Yusuf, Andi Azizah Nurpudji A. Taslim Aryanti Bamahry Devinta Virani Immune Reconstitution Inflamatory Syndrome (IRIS) menggambarkan suatu kumpulan gejala dari kondisi klinis paradoks yang memburuk  pada suatu kondisi yang diketahui atau munculnya suatu kondisi baru setelah memulai terapi Antiretroviral (ARV) dapat disebabkan oleh gangguan non-infeksi dan infeksi mikobakteri, jamur dan atau virus oportunistik. Kami melaporkan kasus seorang wanita, 19 tahun dengan keluhan asupan makan via oral menurun didiagnosis dengan Severe Protein Energy Malnutrition (IMT 12.4 kg/m2) , TB Paru relaps dengan riwayat putus obat dan Immunodeficiency syndrome. Terapi nutrisi diberikan sesuai dengan manajemen refeeding syndrome mulai dari 15 kkal/kg BB dan ditingkatkan bertahap sampai 2000 kkal sesuai dengan kemampuan dan kondisi pasien dengan komposisi protein 1.5 gr/kgBBI/hari, karbohidrat 50-55% dan protein 30-33% diikuti dengan pemberian suplementasi zinc dan vitamin D.  Saat Pasien di Rumah, dilakukan pemantauan selama 5 bulan untuk menilai kondisi klinis, asupan kalori, berat badan dan kapasitas fungsional. Terdapat perbaikan klinis, peningkatan asupan (energi ±2000 kkal), berat badan yang meningkat (IMT 22.37 kg/m2) dan peningkatan kapasitas fungsional (20 kg). Dengan dukungan nutrisi dan dilanjutkan dengan pemberian ARV setelah pengobatan TB paru berlangsung 25 hari, dapat memperbaiki  kondisi dan status metabolisme sehingga mencegah terjadinya IRIS. Perhimpunan Dokter Gizi Klinik Indonesia 2020-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/22 10.54773/ijcnp.v3i1.22 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 3 No. 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 19-28 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 3 No 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 19-28 2775-5215 2597-4297 10.54773/ijcnp.v3i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/22/33

oai:ojs2.journal-ijcnp.com:article/24 2022-12-02T15:56:12Z IJCNP:CR

SUPLEMENTASI MIKRONUTRIEN MENUNJANG EFEKTIVITAS TERAPI GIZI PADA PASIEN AKALASIA ESOFAGUS DENGAN HIPOALBUMINEMIA BERAT St.Pasriany Agussalim Bukhari Haerani Rasyid A. Yasmin Syauki Pendahuluan Akalasia merupakan gangguan motilitas berupa hilangnya peristaltik esofagus dan gagalnya sfingter esofagokardia berelaksasi, makanan tertahan di esophagus. Menyebabkan malnutrisi karena asupan tidak optimal. Laporan Kasus Laki-laki 64 tahun dirawat dikonsul dengan dyspepsia e.c akalasia esofagus. Keluhan utama, asupan makan berkurang dialami sejak 2 bulan karena sulit menelan dan muntah tiap kali makan. Tidak ada nyeri menelan. Demam, batuk dan sesak tidak ada. Ada penurunan berat badan, besarnya tidak diketahui. Luka pada antebrachium dekstra et sinistra. Pasien tidak menderita diabetes maupun hipertensi.  Sakit sedang, GCS E4M6V5, tanda vital normal. Status gizi severe protein energy malnutrition berdasarkan ukuran LILA (18 cm). Hasil laboratorium didapatkan deplesi berat sistem imun, hipoalbuminemia dan penurunan fungsi ginjal. Terapi nutrisi berupa diet 1430 kkal, protein 1.2g/kgBBI/hari dalam bentuk makanan cair via oral dan nutrisi parenteral. Kebutuhan cairan 1400ml/24 jam. Suplementasi vitamin B kompleks, zinc 20mg, pujimin 450mg, vitamin A 20.000IU, Vitamin C 300mg dan Curcuma 400 mg/8jam. Pemantauan asupan, toleransi saluran cerna, tanda vital dan keseimbangan cairan setiap hari. Setelah perawatan 41 hari, pasien dapat menelan makanan lunak, luka pada antebrachium menutup, tidak terjadi perburukan status gizi, albumin dan protein total meningkat.   Kesimpulan Hipoalbuminemia pada pasien akalasia esofagus, efusi pleura bilateral, skin and soft tissue infection terkoreksi dengan asupan protein 1,2 gr/kgBBI/hari, Zinc 20 mg, vitamin B kompleks, Pujimin 450 mg, Vitamin A 20.000 IU, Vitamin C 300 mg dan Curcuma 400 mg/8 jam/oral. Perhimpunan Dokter Gizi Klinik Indonesia 2018-10-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/24 10.54773/ijcnp.v1i1.24 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 1 No. 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 1-9 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 1 No 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 1-9 2775-5215 2597-4297 10.54773/ijcnp.v1i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/24/12

oai:ojs2.journal-ijcnp.com:article/25 2022-12-02T15:56:12Z IJCNP:CR

EDUKASI GIZI SEBAGAI SALAH SATU MODALITAS TERAPI MEMPENGARUHI SURVIVAL RATE PASIEN DENGAN NEOPLASMA OVARIUM KISTIK Cecy Rahma Karim As’ad, Suryani Nurpudji A Taslim Mardiana Madjid Pendahuluan Kanker ovarium adalah proses keganasan primer yang terjadi pada organ ovarium. Keganasan ovarium dapat terjadi pada seluruh usia kehidupan wanita. Malnutrisi pada penderita kanker secara negatif berpengaruh terhadap respon terapi, komplikasi, kualitas hidup dan survival penderita. Intervensi nutrisi dapat mencegah malnutrisi. Laporan kasus Seorang perempuan dengan diagnosa neoplasma ovarium stadium IV A dengan efusi pleura dan asites yang direncanakan untuk dioperasi. Pasien mengeluh asupan tidak adekuat karena terasa cepat kenyang dan terjadi penurunan berat badan selama 8 bulan sebesar 6 kg. Pemeriksaan fisik ditemukan pasien tampak anemis,loss of subcutaneous fat,asites,muscle wasting ada. Pada laboratorium menunjukkan penurunan kadar hemoglobin dan albumin,peningkatan kadar leukosit. Pasien di diagnosa dengan gizi buruk,anemia normositik normokrom,deplesi sistem imun, hipoalbuminemia, dan leukositosis. Total kebutuhan energi terkoreksi adalah 1450 kkal dengan komposisi protein 19.8 % karbohidrat 50-55% dan lemak 25-30%, yang ditingkatkan bertahap. Intervensi nutrisi diberikan melalui oral berupa makanan lunak dan formula tinggi protein, kebutuhan cairan 1000 ml/hr,diberikan suplementasi multivitamin neurodex,vitamin C 100 mg,vitamin A 6000 IU,zink 20 mg, dan kapsul ikan gabus 3x2 kapsul setiap hari. Setelah 11 hari intervensi nutrisi pasien menunjukkan perbaikan pada hemoglobin, albumin dan lekosit dan kondisi pasien mengalami perbaikan sehingga operasi dapat dilakukan. Kesimpulan Intervensi nutrisi; makro dan mikronutrien, monitoring serta edukasi gizi diperlukan untuk menunjang perbaikan kondisi klinis pasien. Perhimpunan Dokter Gizi Klinik Indonesia 2018-10-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/25 10.54773/ijcnp.v1i1.25 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 1 No. 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 10-17 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 1 No 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 10-17 2775-5215 2597-4297 10.54773/ijcnp.v1i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/25/13

oai:ojs2.journal-ijcnp.com:article/27 2022-12-02T15:56:11Z IJCNP:CR

PERBAIKAN KADAR ALBUMIN PASIEN POST AMPUTASI ET CAUSA LUKA BAKAR LISTRIK 25% DERAJAT III DAN STATUS GIZI KURANG DENGAN PEMBERIAN ASUPAN TINGGI PROTEIN Diane Paparang Nurpudji A. Taslim Haerani Rasyid A. Yasmin Syauki Pendahuluan Proses penyembuhan luka post amputasi dan luka bakar dengan luas 25% dan kedalaman derajat III serta hipoalbuminemia sedang (albumin 2,6g/dL) dan status gizi kurang memerlukan terapi gizi spesifik tinggi protein. Laporan Kasus Tn.I, laki-laki, 28 tahun dikonsul oleh bagian bedah dengan luka post amputasi dan  luka bakar listrik derajat III luas 25%. Keluhan utama asupan makan kurang sejak 16 hari terakhir karena nafsu makan kurang akibat nyeri pada luka post amputasi dan luka bakar. Ada nyeri ulu hati dan demam menggigil. Asupan 24 jam 1000kkal. Pasien didiagnosis dengan status gizi kurang (LLA=80,7%), status metabolik anemia normositik normokrom (Hb 9.7 g/dl), deplesi sedang sistem imun (TLC 940/µL), hipoalbuminemia (albumin 2,6g/dL) dan status gastrointestinal fungsional. Terapi nutrisi dengan energi 2500 kkal, protein 2 gr/kgBBI/hari (23%), karbohidrat 57% dan lemak 20 %, melalui oral berupa makanan biasa 1250 kkal, ONS glutamine 2.5g/hari, suplementasi 6 butir putih telur (protein 31,5g/hari), vitamin C 1g/24jam, vitamin A 6.000IU/12jam, vitamin B1-100mg, vitamin B6-200mg, vitamin B12-200mg, Zinc 50mg/24jam, selenium 55µg, Curcuma 400mg/8jam dan ekstrak ikan gabus 2 kapsul/8 jam. Setelah perawatan 30 hari, terjadi perbaikan dalam penyembuhan luka, peningkatan LLA menjadi 23,5cm, peningkatan hemoglobin 9.3g/dl, peningkatan sistem imun (TLC 2064/µL), peningkatan albumin 3.9g/dL. Kesimpulan Terapi nutrisi spesifik dengan protein 2 gr/kgBBI dapat meningkatkan kadar albumin dan mempercepat penyembuhan luka pada pasien luka bakar. Perhimpunan Dokter Gizi Klinik Indonesia 2018-10-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/27 10.54773/ijcnp.v1i1.27 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 1 No. 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 18-25 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 1 No 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 18-25 2775-5215 2597-4297 10.54773/ijcnp.v1i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/27/14

oai:ojs2.journal-ijcnp.com:article/28 2022-12-02T15:56:11Z IJCNP:CR

KECUKUPAN KALORI MENUNJANG PERBAIKAN IMBALANCE ELEKTROLIT PADA PASIEN DENGAN KARSINOMA BULI Josefina Junizar Nurpudji A Taslim Suryani As’ad Mardiana Madjid Pendahuluan Karsinoma buli merupakan jenis kanker yang dimulai di kandung kemih. Insiden karsinoma buli tahun 2000 di Amerika Serikat diperkirakan sebanyak 53.200 orang. Karsinoma buli merupakan keganasan terbanyak nomor 4 pada pria. Laporan Kasus Seorang laki-laki berusia 30 tahun dikonsul dengan diagnosa medis tumor buli-buli metastase ke hepar dan pulmo, intake inadekuat, cancer paru dan DIC. Pasien dikonsulkan karena asupan makan berkurang sejak 3 hari lalu karena merasa mengganjal di tenggorokan, nafsu makan menurun, ada rasa nyeri uluhati dan sakit perut. Asupan 24 jam 52,5 kkal. Pasien didiagnosis dengan status gizi buruk (LLA 68%), status metabolik anemia (Hb 8,9g/dl), hipoalbuminemia (albumin 3,3g/dl), hypokalemia (3,3g/dl), penurunan fungsi ginjal (ureum 64mg/dl, kreatinin 1,82mg/dl), dan status gastrointestinal fungsional. Terapi nutrisi dengan energi 1080 kkal deinaikkan bertahap sesuai toleransi pasien sampai 2700 kkal, protein 1g/kgBBI/hari dinaikkan sampai 2g/kgBBI/hari, karbohidrat 60% dan lemak 31% melalui oral awalnya kemudian pasang NGT berupa makanan lunak selanjutnya bubur saring, formula nefrisol, jus buah dan putih telur 6 butir/hari, zinc 20mg/24jam, neurodex 1tablet/24jam, KSR 600mg/24jam dan ekstrak ikan gabus 2kapsul/8jam. Setelah perawatan 18 hari, status gizi masih buruk. Kesimpulan Dukungan nutrisi yang optimal dan monitoring pada pasien kanker menunjukkan perbaikan status gizi, perbaikan status metabolik sehingga dapat mempercepat proses perbaikan keadaan umum. Perhimpunan Dokter Gizi Klinik Indonesia 2018-10-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/28 10.54773/ijcnp.v1i1.28 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 1 No. 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 26-36 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 1 No 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 26-36 2775-5215 2597-4297 10.54773/ijcnp.v1i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/28/15

oai:ojs2.journal-ijcnp.com:article/29 2022-12-02T15:56:10Z IJCNP:CR

PEMBERIAN PROTEIN YANG ADEKUAT MEMPERCEPAT PENUTUPAN BURST ABDOMEN PADA PASIEN GERIATRI DENGAN TUMOR KOLON Rosdiana R Agussalim Bukhari Nurpudji A Taslim Mardiana Madjid Pendahuluan Burst abdomen adalah terpisahnya jahitan luka pada abdomen secara parsial atau komplit salah satu atau seluruh lapisan dinding abdomen pada luka post operatif disertai protrusi dan eviserasi isi abdomen yang merupakan komplikasi tindakan bedah karena tidak adekuatnya perawatan luka, pengobatan, dan dukungan nutrisi. Resume kasus Seorang laki-laki berumur 85 tahun, dikonsul  dari bagian bedah digestif dengan diagnosis medis Burst abdomen post operasi laparatomi dan colostomi et causa tumor colon rectosigmoid, keluhan utama luka terbuka  di perut dan asupan tidak adekuat, Riwayat penurunan berat badan kurang dari 5 kg selama 1 bulan terakhir. Buang air besar via colostomi. Pemeriksaan antropometri didapatkan LLA 18 cm. Pada pemeriksaan fisik ditemukan, anemia (+), Loss of subcutaneus fat (+), terdapat wasting pada keempat ekstremitas. Pemeriksaan laboratorium didapatkan deplesi berat sistem imun (874), hipoalbuminemia (2.6), anemia (9.6) dan hipokalemia (2.9). Kebutuhan Energi Terkoreksi : 1394 kkal dengan komposisi makronutrien: Protein: 1,7 gr/kg BBI/hari = 79.92 gr =22%, Karbohidrat : 55%= 192,5 gr, Lemak : 23% = 35,7gr. Penatalaksanaan nutrisi perioperatif  yang diberikan bertujuan sebagai manajemen nutrisi perioperatif, meningkatkan status gizi dan memperbaiki status metabolik pasien, mempercepat penyembuhan luka dan memberikan edukasi gizi ke pasien. Operasi repair wound dilakukan dengan nilai PNI 36,5.Pada hari ke-13 post operasi terjadi dehisensi luka. Peningkatan pemberian protein sebesar 2 gram /kgBBI/hari karena tidak adanya peningkatan kadar albumin. Setelah diintervensi pada hari ke 35 post operasi mulai terjadi perbaikan  luka operasi. Pada pasien ini juga dilakukan program peningkatan berat badan( penambahan kalori secara bertahap dengan maksimal pemberian sebesar 1000 kkal) untuk perbaikan status gizi . Pada Monitoring dan evaluasi  asupan membaik, antropometri terjadi peningkatan (LLA 20,5cm)dan pada pemeriksaan laboratorium didapatkan perbaikan kadar TLC (2.769), albumin (3,8) dan kalium (5,3) serta  kadar Hb (11).Lama perawatan perioperatif 100 hari. Kesimpulan Intervensi nutrisi yang optimal, monitoring serta edukasi gizi diperlukan untuk menunjang perbaikan kondisi klinis pasien pre dan post operatif dengan burst abdomen. Intervensi nutrisi yang optimal, monitoring serta edukasi gizi yang baik menunjukkan adanya perbaikan asupan kalori, status metabolik sehingga dapat mengurangi risiko infeksi, lama rawat dan mortalitas yang berefek pada perbaikan luka. Perhimpunan Dokter Gizi Klinik Indonesia 2018-10-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/29 10.54773/ijcnp.v1i1.29 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 1 No. 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 37-47 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 1 No 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 37-47 2775-5215 2597-4297 10.54773/ijcnp.v1i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/29/16

oai:ojs2.journal-ijcnp.com:article/30 2022-12-02T14:00:45Z IJCNP:CR

PEMBERIAN NUTRISI ENTERAL DAPAT MEMPERTAHANKAN KADAR ALBUMIN NORMAL NAMUN TIDAK MEMPERBAIKI KADAR TLC PADA PASIEN KARSINOMA NASOFARING Lusi Makaba Suryani As’ad Nurpudji A Taslim A. Yasmin Syauki Pendahuluan Malnutrisi pada keganasan kepala dan leher sering terjadi yang ditandai dengan penurunan berat badan 10% selama menjalani terapi. Intervensi nutrisi dapat mencegah malnutrisi. Laporan Kasus Tn.M, umur 35 tahun dikonsulkan dari THT-KL dengan diagnosa karsinoma nasofaring stadium IV B dengan keluhan utama sulit  menelan selama 2 hari sebelum dikonsul dan penurunan berat badan dalam 2 minggu. Pemeriksaan Antropometri: panjang badan: 171 cm, lingkar lengan atas: 22 cm, berat badan ideal: 63,9 kg, berat badan aktual: 45 kg, indeks masa tubuh:15,3 kg/m2. Pemeriksaan fisik didapatkan: massa tumor pada leher kanan, kehilangan lemak subkutan, muscle wasting. Status gizi: gizi buruk. Pemeriksaan laboratorium: kolesterol total 224 mg/dL,LDL190 mg/dL. Intervensi nutrisi dengan kebutuhan energi terkoreksi 2200 kkal dengan komposisi  karbohidrat 50 %, protein 17% dan  lemak 33 %. Diet diberikan 50 % via nasogastric tube berupa makanan saring, susu formula, jus buah. Selanjutnya, diet akan ditingkatkan sesuai toleransi sampai kebutuhan energi terkoreksi tercapai. Setelah perawatan 14 hari, pada pasien ini terjadi peningkatan lingkar lengan atas pada awal perawatan 22 cm menjadi 22.5 cm, berat badan aktual 45 kg menjadi 46 kg. Hasil laboratorium didapatkan perbaikan profil lipid. Kesimpulan Terapi nutrisi pada pasien karsinoma nasofaring dengan gizi buruk dapat meningkatkan berat badan dan mencegah adanya malnutrisi energi-protein yang berat. Perhimpunan Dokter Gizi Klinik Indonesia 2018-10-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/30 10.54773/ijcnp.v1i1.30 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 1 No. 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 48-56 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 1 No 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 48-56 2775-5215 2597-4297 10.54773/ijcnp.v1i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/30/17

oai:ojs2.journal-ijcnp.com:article/31 2022-12-02T15:56:10Z IJCNP:CR

PENGARUH GIZI TERHADAP RESPON TERAPI PASIEN CHRONIC MYELOCYSTIC LEUKIMIA (CML) Asrini Safitri Haerani Rasyid Agussalim Bukhari Mardiana Madjid Latar Belakang Penyakit kanker darah atau yang sering disebut dengan leukemia adalah salah satu penyakit yang mematikan. Penyakit ini merupakan kurangnya sel darah merah pada system produksi darah di tubuh manusia dan memproduksi sel darah putih dengan jumlah yang berlebihan. Laporan Kasus Tn I, Laki-laki, 37 tahun dikonsul oleh bagian Interna dengan Chronic Myelocystic Leukimia. Keluhan utama Asupan makan berkurang dialami sejak 5 bulan yang lalu dan memberat dalam 2 bulan terakhir karena nafsu makan menurun, mual  , tidak muntah, riwayat muntah ada, Ada gangguan menelan  ,rasa cepat kenyang , ada demam ,ada riwayat demam , batuk, tidak  sesak, penurunan berat badan ada tetapi besarnya tidak diketahui. Asupan 24 jam 550 Kkal. Pasien didiagnosis dengan status gizi buruk ( LLA = 59,32%), status metabolik anemia normositik normokrom (Hb 7,9 g/dl ),  Hipoalbuminemia  ( Albumin 2,9 gr/dl ), Hipoglikemia ( GDS 67 mg/dl ), leukositosis ( 53.550 /uL ) , dan status gastrointestinal fungsional. Penatalaksanaan Nutrisi dengan pemberian Energi 1600 Kkal yang diberikan secara bertahap sesuai toleransi pasien dan manajemen peningkatan berat badan dilakukan bertahap jika kebutuhan energi telah tercapai. Protein diberikan 1,5 gram/KgBBI/ hari ( 19%), Karbohidrat 50% dan lemak 31%. Pemberian asupan via oral berupa makanan lunak, formula peptisol, buah, dan putih telur 3 butir / hari. Suplementasi diberikan berupa zinc 20 mg/24 jam, Curcuma 40 mg/8 jam, ekstrak ikan gabus 2 kapsul/8 jam, Vitamin B1 100 mg, Vitamin B6 200 mg, Vitamin B12 200 mg, Vitamin C 100 mg/24 jam. Setelah perawatan selama 16 hari, terjadi peningkatan LLA dari 17,5 cm menjadi 19 cm, Hb 7,9 gr/dl menjadi 11,9 gr/dl dengan transfusi PRC 3 kantong. Kadar sel darah putih saat masuk rumah sakit adalah 53.550/uL dan saat dipulangkan 29.000/uL . Pada saat awal di rawat, kadar albumin pasien adalah 2,9 g/dL. Kemudian turun menjadi 2.5 g/dL. Pada saat albumin turun menjadi 2.5 g/dL, pasien di anjurkan untuk mengkonsumsi makanan yang tinggi protein, memberikan formula tinggi protein dan pemberian ekstra putih telur dan setelahnya kadar albumin pasien naik menjadi 3.2 g/dL sebelum dipulangkan untuk rawat jalan. Kesimpulan Malnutrisi pada penderita kanker secara negatif berpengaruh terhadap respon terapi, komplikasi, kualitas hidup dan survival penderita. Intervensi nutrisi yang optimal, monitoring serta edukasi gizi menunjukkan perbaikan status gizi serta perbaikan status metabolik. Perhimpunan Dokter Gizi Klinik Indonesia 2018-10-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/31 10.54773/ijcnp.v1i1.31 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 1 No. 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 57-66 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 1 No 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 57-66 2775-5215 2597-4297 10.54773/ijcnp.v1i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/31/18

oai:ojs2.journal-ijcnp.com:article/32 2022-12-02T15:56:09Z IJCNP:CR

PERANAN ANTIOKSIDANT DALAM MENAIKKAN NAFSU MAKAN PASIEN TUMOR PANCREAS DISERTAI GIZI BURUK Umrayani Agussalim Bukhari Suryani As’ad Mardiana Madjid Latar Belakang Tumor pankreas merupakan jenis tumor yang dapat mengenai pankreas baik jaringan eksokrin maupun endokrin.  Sebanyak 90% merupakan tumor ganas jenis adenokarsinoma ductal pankreas yang merupakan neoplasma primer dimana frekuensinya 80% dari semua keganasan pankreas. Laporan kasus Seorang laki-laki umur 41 tahun  dikonsul dari bagian bedah dengan diagnosis  Post operasi laparatomi eksplorasi bypass biliodigestif  choledocho-jejunostomy. Keluhan utama nafsu makan berkurang, Dialami sejak ± 17 hari. Ada  mual dan muntah tiap kali makan, nyeri perut dan nyeri luka operasi.  Riwayat makan makanan berlemak tinggi ada, merokok ada, riwayat minum alkohol ada. Pemeriksaan fisis  ditemukan konjungtiva anemis, sclera sub ikterik, thorax ada loss of subcutaneous fat,  ekstremitas ada wasting dan edema dorsum pedis. Pasien didiagnosis dengan Severe Protein Energy Malnutrition ( 64% Lila), status metabolic anemia normositik normokrom (9,4 g/dl), leukositosis (17600), hipoalbuminemia (2,3), hiponatremia (132), Hipocloremia (94). Penatalaksanaan nutrisi dengan energi 1600 kkal, karbohidrat 55%.  Protein yang diberikan 1,5 g/kgBB/hari, lemak 24% melalui oral berupa makanan lunak, formula peptisol, buah, dan putih telur 2 butir perhari, diberikan kapsul ekstrak ikan gabus 2 kapsul/8 jam, zamel syrup 2 sendok/8 jam. Dan curcuma 400 mg/8jam. Kesimpulan Intervensi nutrisi yang optimal, monitoring serta edukasi gizi diperlukan untuk menunjang perbaikan kondisi klinis pasien kanker pankreas disertai dengan gizi buruk dan hipoalbuminemia. Perhimpunan Dokter Gizi Klinik Indonesia 2018-10-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/32 10.54773/ijcnp.v1i1.32 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 1 No. 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 67-73 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 1 No 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 67-73 2775-5215 2597-4297 10.54773/ijcnp.v1i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/32/19

oai:ojs2.journal-ijcnp.com:article/33 2022-12-02T15:56:09Z IJCNP:CR

PERBAIKAN ANEMIA PADA PASIEN HIV STADIUM III DAN STATUS GIZI KURANG DENGAN PEMBERIAN ASUPAN TINGGI PROTEIN DAN MULTIPLE MICRONUTRIENT SUPPLEMENT Maria Ingrid Budiman Agussalim Bukhari R Sutrisno A. Yasmin Syauki Latar Belakang Anemia normositik normokrom terjadi pada 60% hingga 80% pasien HIV. Anemia dapat menurunkan survival, mempercepat progresivitas penyakit, dan meningkatkan mortalitas pada pasien HIV. Pemberian asupan tinggi protein dan multiple micronutrient supplement diperlukan untuk memperbaiki kadar hemoglobin dan mencegah perburukan anemia. Laporan Kasus Seorang pasien berjenis kelamin laki-laki, umur 25 tahun dikonsulkan dari bagian penyakit dalam dengan diagnosis HIV stadium III untuk terapi nutrisi. Keluhan utama asupan makan berkurang sejak satu bulan terakhir akibat nafsu makan berkurang. Pasien mengeluh batuk, sesak, dan demam.  Pasien tersebut memiliki riwayat berganti pasangan, dan sedang dalam pengobatan OAT hari ketiga. Asupan 24 jam 769 kkal. Dari pemeriksaan laboratorium, didapatkan anemia (Hb 9,5 g/dl), deplesi berat sistem imun (TLC 613/µL), dan hipoalbuminemia (2,1 g/dl). Status gizi pasien ini adalah gizi kurang berdasarkan ukuran lingkar lengan atas (73% LLA). Terapi nutrisi diberikan melalui oral dengan energi 2200 kkal, protein 2gr/kgBBI/hari(17%), karbohidrat 50% dan lemak 33% berupa makanan lunak, buah, dan susu formula. Suplementasi yang diberikan adalah zinc 20mg/24jam, vitamin A 6000/24jam, vitamin B1 100 mg/24jam, vitamin B6 200 mg/24jam, vitamin B12 200 µg/24jam, vitamin C100mg/24jam, dan ekstrak ikan gabus 2kapsul/8jam. Setelah perawatan selama 13 hari, pasien dipulangkan dengan status gizi: gizi kurang (IMT 18,36kg/m2), anemia (Hb 11,6 g/dl), deplesi berat sistem imun (TLC 462/µL), dan hipoalbuminemia (3,1 g/dl).  Kesimpulan Terapi nutrisi yang adekuat dapat memperbaiki anemia pasien HIV stadium III. Perhimpunan Dokter Gizi Klinik Indonesia 2018-10-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/33 10.54773/ijcnp.v1i1.33 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 1 No. 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 74-79 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 1 No 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 74-79 2775-5215 2597-4297 10.54773/ijcnp.v1i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/33/20

oai:ojs2.journal-ijcnp.com:article/34 2022-12-02T15:56:09Z IJCNP:CR

MENURUNKAN INFLAMASI PASIEN SLE DAN GIZI BURUK DENGAN SUPLEMENTASI MIKRONUTRIEN Mia Miranda Haerani Rasyid Agussalim Bukhari Aryanti R. Bamahry Latar Belakang Lupus eritematosus sistemik (Systemic Lupus Erythematosus)(SLE) merupakan penyakit inflamasi autoimun kronis dengan etiologi yang belum diketahui serta manifestasi klinis. Laporan Kasus Nn.M, Perempuan, 20 Tahun dikonsul dengan bagian penyakit bagian Interna divisi Ginjal Hipertensi untuk evaluasi dan penatalaksanaan gizi serta rawat bersama dengan diagnosis medis Sistemik Lupus Eritematosus dan anoreksia Asupan makan berkurang dialami sejak 2 minggu yang lalu karena tidak ada nafsu makan. Mual ada setiap kali makan, muntah tidak ada, nyeri ulu hati ada, demam tidak ada, riwayat demam ada terutama malam hari, badan lemas,tidak mampu berdiri maupun duduk sendiri, batuk ada sejak 2 minggu, lendir ada. Penurunan berat badan ada ±4 kg dalam 2 minggu(BB dulu 35 kg). Asupan 24 jam 97,5 kkal. Pasien didiagnosis dengan status gizi buruk, status metabolik anemia (Hb 6,2 g/dl), deplesi berat sistem imun (TLC 400/uL), Hipertrigliseridemia 236 mg/dl, risiko refeeding, hipoalbumin berat 2.2 g/dl dan status gastrointestinal fungsional. Penatalaksanaan nutrisi dengan target awal energi 2000 kkal, oleh karena pasien dengan resiko refeeding maka dilakukan penatalaksanaan nutrisi 10-15 kkal/hari selama 3 hari  dengan pemberian thiamin 300 mg/hari serta perbaikan kadar kalium darah. Setelah terlewati 3 hari , nutrisi dinaikkan sesuai toleransi pasien sampai 2500 kkal dengan komposisi protein 2 gr/kg BBI/hari(16%), karbohidrat 60%, lemak 24% melalui oral berupa makanan lunak sesuai toleransi, formula nutrican, jus buah tinggi kalium, madu,  dan olive oil, zink 20 mg/24 jam, Ca hydrogen phosphate 400 mg, Ca laktat 200 mg, Vitamin B6 40 mg, Vitamin C 50 mg, Vitamin D3 200 IU, fish oil(EPA) 2000 mg/24 jam, ekstrak ikan gabus 3 kapsul/8 jam. Setelah 15 hari perawatan, status gizi buruk dengan perbaikan pasien secara klinis(IMT 14,5 kg/m2), hemoglobin 10.7 g/dl, deplesi berat sistem imun (TLC 600/uL), hipoalbumin ringan 3.1 gr/dL. Kesimpulan Dukungan nutrisi optimal dapat membantu untuk mengendalikan inflamasi yang ditemukan akibat penyakit SLE dan komplikasi yang disebabkan efek samping pengobatan. Perhimpunan Dokter Gizi Klinik Indonesia 2018-10-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/34 10.54773/ijcnp.v1i1.34 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 1 No. 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 80-89 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 1 No 1 (2018): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 80-89 2775-5215 2597-4297 10.54773/ijcnp.v1i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/34/21

oai:ojs2.journal-ijcnp.com:article/37 2022-12-02T15:56:04Z IJCNP:RA

PERBANDINGAN STATUS GIZI MENURUT PENGUKURAN INDEKS MASSA TUBUH DAN PENGUKURAN PERSENTASE LEMAK TUBUH MENGGUNAKAN DXA SCAN DI RUMAH SAKIT X PEKANBARU Lumban Toruan, Rahel Christianto, Erwin Masdar, Huriatul Background Obesity can occur due to the accumulation of excess fat in the body.Obesity has been declared as a global epidemic by the World Health Organization (WHO). In 2016, more than 1,9 billions adults were overweight. In 2018, it was found that 24,1% of adults in Riau Province were obese with an incidence higher in women than men. Research Objectives This research is an analytical study to determine the comparison of nutritional status based on the data that has been collected from body mass index (BMI) measurement and body fat percentage measurement by DXA Scan, which was carried out on 364 adults aged 19-65 years. Metodology The data that has been obtained from BMI measurement will be grouped to four categories and the data that has been obtained from body fat percentage will be grouped to five categories based on their gender. The bivariate analysis using paired T Test will be done to see the p value. Conclusion From this study, it was found that most of the  subjects were obese. According to the BMI examination, about 50,27% of the subjects were  categorized as obese. Meanwhile, according to the body fat percentage measurement using DXA Scan, about 89,56% of subjects were included in the obese category. Based on the p value of 0,001 that obtained from the paired t test, it can be concluded that there are significant differences between these two methods.   Keywords : BMI, DXA Scan, nutritional status, obese Perhimpunan Dokter Gizi Klinik Indonesia 2020-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/37 10.54773/ijcnp.v3i1.37 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 3 No. 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 80-88 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 3 No 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 80-88 2775-5215 2597-4297 10.54773/ijcnp.v3i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/37/42

oai:ojs2.journal-ijcnp.com:article/40 2022-12-02T15:56:04Z IJCNP:RA

ASTAXANTHIN MENGHAMBAT PERLEMAKAN HATI DAN PENINGKATAN KADAR SERUM GAMMA-GLUTAMYLTRANSFERASE PADA TIKUS WISTAR JANTAN YANG DIBERI MINYAK JELANTAH Pangalela, Astrid Amanda I Wayan Weta Iin Indrayani Maker ABSTRACT Non-alcoholic fatty liver can be triggered by used cooking oil consumption due to the formation of free radicals and the accumulation of fatty acids in the body. Astaxanthin is a powerful antioxidant that may be able to inhibit the pathogenesis of fatty liver. This study aims to determine the effect of astaxanthin in inhibiting fatty liver (steatosis) and levels of Gamma-Glutamyltransferase (GGT) in male Wistar rats given used cooking oil. An experimental study with Post-test Only Control Group Design was conducted on 36 male Wistar rats aged 3.5-4 months with an approximate bodyweight of 200-210 grams divided randomly into 2 groups. The control group was given 0.42 ml of used cooking oil + 0.5 ml of distilled water, and the treatment group was given 0.42 ml of used cooking oil + 0.2 mg of astaxanthin each day for 14 days. On day 15, blood tests and hepatic histopathology were performed to check  GGT serum levels and steatosis. The comparative test was conducted to compare the results of the control and treatment groups. The results showed that the mean steatosis and GGT levels in the treatment group were significantly lower than the control group. It can be concluded that giving astaxanthin can inhibit fatty liver (steatosis) and increase GGT serum levels in male Wistar rats given used cooking oil.   Keywords: Astaxanthin, Fatty liver, Gamma-glutamyltransferase, Used cooking oil Perhimpunan Dokter Gizi Klinik Indonesia 2020-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/40 10.54773/ijcnp.v3i1.40 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 3 No. 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 46-55 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 3 No 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 46-55 2775-5215 2597-4297 10.54773/ijcnp.v3i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/40/36

oai:ojs2.journal-ijcnp.com:article/42 2022-12-02T15:56:03Z IJCNP:RA

ASTAXANTHIN MENGHAMBAT PENURUNAN JUMLAH SEL LEYDIG DAN KADAR TESTOSTERON PADA TIKUS WISTAR JANTAN YANG DIPAPAR DENGAN ASAP ROKOK Lie, Andrew Pangkahila, Wimpie Maker, L.P. Iin Indrayani Background. The exposure of cigarette smoke impacts negatively on Leydig cell count and testosterone level. Astaxanthin is known for its ability to neutralize free radicals far more potent than any other kind of antioxidant. Research objectives. This research aims to prove the effect of Astaxanthin in inhibiting decrease of Leydig cell count and testosterone level in male Wistar rats exposed with cigarette smoke. Methodology. The posttest only control group study design was conducted on 36 male Wistar rats, 12-16 weeks in age, with 200-210 grams body weight. Samples were randomly divided into two groups, consisting of a control group exposed with cigarette smoke and 0.5 ml of aquadest and a study group exposed with cigarette smoke and 0.1 mg of astaxanthin/200 gr BW daily for 30 days. On day 31, blood samples were taken to measure the testosterone level. Both testes were taken for Leydig cells count assessment. Comparative analysis was done to see any significant difference between the study and control group. Research results. The results show that the mean number of Leydig cells and testosterone levels in the study group was significantly higher than the control group (p<0.01). Conclusion. Oral astaxanthin administration inhibited the decrease of Leydig cell count and testosterone level in male Wistar rats exposed with cigarette smoke. Key words: Astaxanthin, Testosterone, Leydig Cell, Andropause Perhimpunan Dokter Gizi Klinik Indonesia 2020-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/42 10.54773/ijcnp.v3i1.42 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 3 No. 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 56-64 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 3 No 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 56-64 2775-5215 2597-4297 10.54773/ijcnp.v3i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/42/37

oai:ojs2.journal-ijcnp.com:article/52 2022-12-02T15:56:03Z IJCNP:CR

ANOREKSIA SEBAGAI SALAH SATU MANIFESTASI KLINIS PADA PASIEN DENGAN TUMOR REGIO SUPRASELLAR Feraldho, Andrea Putri, Gabriella Nurahmani Darmoutomo, Endang Malnutrisi pada tumor disebabkan oleh inflamasi sistemik yang menyebabkan proteolisis, lipolisis dan anoreksia. Meski anoreksia pada tumor sering dikaitkan dengan adanya inflamasi, penekanan pada hipotalamus karena tumor juga dapat menyebabkan anoreksia. Studi kasus pada anak usia 11 tahun 5 bulan yang dikonsultasikan dengan lemas, malnutrisi berat dan kolelitiasis. Pasien mengalami mual, muntah, tidak nafsu makan, dan penurunan berat badan (BB) sebanyak 12 kg sejak 2 bulan sebelum masuk rumah sakit. Asupan per 24 jam sebanyak 150 kkal. BB pasien 18 kg, tinggi badan (TB) 123 cm, indeks massa tubuh (IMT) 11.9 kg/m2. Hasil MRI kepala menunjukan adanya massa pada regio suprasellar, suspek germinoma. Pasien didiagnosa dengan tumor suprasellar, gizi buruk (skor-z IMT untuk usia (IMT/U) -4.19) dan perawakan sangat pendek (skor-z TB untuk usia -3.33). Diagnosa metabolisme adalah hipermetabolisme dan status gastrointestinal fungsional. Terapi nutrisi diberikan berdasarkan tatalaksana malnutrisi anak oleh World Health Organization (WHO). Target awal pemberian nutrisi adalah 1500 kkal/hari (83 kkal/kgBB/hari). Pemberian dimulai dari 600 kkal/hari, lalu ditingkatkan bertahap hingga mencapai 2700 kkal/hari (123 kkal/kgBB/hari). Pasien pulang dengan peningkatan berat badan sebanyak 4.3 kg, IMT 14.7 kg/m2, skor-z -1.53, status gizi kurang gizi. Berkurangnya ukuran massa tumor diikuti dengan peningkatan nafsu makan. Perhimpunan Dokter Gizi Klinik Indonesia 2021-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/52 10.54773/ijcnp.v4i1.52 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 4 No. 1 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 12-23 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 4 No 1 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 12-23 2775-5215 2597-4297 10.54773/ijcnp.v4i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/52/40

oai:ojs2.journal-ijcnp.com:article/54 2024-04-01T12:46:17Z IJCNP:CR

POLA PEMBERIAN MAKAN PADA BALITA STUNTING BERDASARKAN TEORI TRANSCULTURAL NURSING Ina, Risnah Lestari, Bunga Sutria, Eny Irwan, Muhammad Balita stunting menjadi masalah kesehatan penduduk dunia.  Pola pemberian makan yang diberikan dalam keluarga berkaitan erat dengan nilai budaya keluarga dan bagaimana pola perilaku hidup sehatnya. Penelitian ini merupakan tinjauan literatur yang bertujuan menganalisis faktor pemberian makan oleh keluarga pada balita stunting berdasarkan teori transcultural nursing. Metode pencarian artikel dalam penelitian ini yaitu menggunakan 4 database yakni proquest, pubmed, DOAJ dan Scholar. Cara mencari artikel berkualitas, penulis menggunakan instrumen critical appraisal dari Joanna Briggs Institute yang memuat ceklist dan tool critical appraisal. Manggunakan kata kunci pola pemberian makan, balita stunting dan transcultural nursing. Hasilnya yakni  pencarian mengunakan database proquest ditemukan 1 artikel, pencarian menggunakana database Pubmed ditemukan 110 artikel, pencaian menggunakan database DOAJ ditemukan  36 artikel dan pencarian menggunkan database Scholar ditemukan 87 artikel. Secara keseluruhan ditemukan 234 artikel yang akan diseleksi melalui kriteria inklusi dan ekslusi sehingga akan ditemukan kriteria artikel yang akan direview terkait penelitian ini. Artikel yang membahas mengenai pemberian pola makan pada balita stunting ditemukan 188 artikel sedangkan artikel yang membahas tentang teori transcultural nursing ditemukan 45 artikel dan artikel yang sesuai dengan judul penelitian ditemukan 10 artikel. Disimpulkan bahwa faktor nilai budaya dan gaya hidup mempengaruhi pola pemberian makan balita stunting. Perhimpunan Dokter Gizi Klinik Indonesia 2021-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/54 10.54773/ijcnp.v4i1.54 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 4 No. 1 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 36-45 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 4 No 1 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 36-45 2775-5215 2597-4297 10.54773/ijcnp.v4i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/54/45

oai:ojs2.journal-ijcnp.com:article/55 2022-12-02T15:56:02Z IJCNP:CR

TERAPI NUTRISI PADA NEFROPATI DIABETIK, GAGAL JANTUNG KRONIK NYHA III, KARSINOMA SERVIKS, POST OPERASI URS BILATERAL, REPLACE DJ STENT Ismail, Andi Syurma Sari Bukhari, Agussalim Nefropati Diabetik or Diabetic Kidney Disease (DKD) adalah perubahan struktural dan fungsional patologis spesifik yang terlihat pada ginjal pasien Diabetes Mellitus (DM). Nefropati diabetik menyebabkan berbagai perubahan pada kapiler dan arteri, penebalan membran endotel, trombosis dan inflamasi. Kondisi ini terlihat setelah satu atau dua tahun menderita DM. Diabetes mellitus juga dapat berkontribusi pada gagal jantung kronik dengan mekanisme sistemik, miokard, dan seluler. Semua faktor inilah yang dapat menyebakan malnutrisi. Ini adalah laporan kasus dari seorang wanita berusia 50 tahun, dengan keluhan tidak ada asupan oral yang didiagnosis dengan moderate protein energy malnutrition, nefropati diabetik, gagal jantung kronik NYHA III dengan karsinoma serviks dan pasca operasi URS Bilateral, Replace DJ Stent. Terapi nutrisi diberikan 720 kkal, ditingkatkan bertahap menjadi 2000 kkal sesuai kemampuan dan kondisi pasien, dengan komposisi 0,8-1 g / kg BB ideal / hari protein dan ekstrak ikan gabus, 45-50% karbohidrat dan 41-47% lemak diikuti dengan suplementasi seng (20 mg / hari), vitamin B kompleks, dan kurkumin. Terjadi peningkatan asupan energi dari 245 kkal menjadi 2.142,6 kkal diikuti dengan peningkatan hasil laboratorium seperti penurunan ureum / kreatinin (114 / 3,2 menjadi 84 / 2,05 mg / dl, penurunan leukosit (14.000 menjadi 7200 / µl), penurunan asam urat (13,1 hingga 7,3) mg / dl, penurunan kadar gula darah (199 menjadi 162 g / dl), peningkatan hemoglobin (6,7 hingga 8,2 g / dl), peningkatan kadar natrium (128 hingga 131 mmol / l) Kesimpulan: Terapi gizi yang adekuat selama 16 hari dapat memperbaiki kondisi, status metabolisme dan kualitas hidup pasien. Perhimpunan Dokter Gizi Klinik Indonesia 2021-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/55 10.54773/ijcnp.v4i1.55 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 4 No. 1 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 1-11 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 4 No 1 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 1-11 2775-5215 2597-4297 10.54773/ijcnp.v4i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/55/39

oai:ojs2.journal-ijcnp.com:article/59 2022-12-02T15:56:01Z IJCNP:CR

TERAPI NUTRISI PADA PASIEN STENOSIS GASTROJEJUNOSTOMI Jessica, Amelia Audria Graciela Yosua Yan Kristian Yohannessa Wulandari Latar belakang Stenosis merupakan komplikasi yang dapat terjadi pada pembedahan gastrojejunostomi. Stenosis dapat menyebabkan gastric outlet obstruction (GOO), yaitu terhambatnya pengosongan lambung sehingga menimbulkan keluhan mual, muntah, intoleransi terhadap makanan, penurunan selera makan, dan nyeri perut. Gastic outlet obstruction berkepanjangan berisiko menyebabkan terjadinya dehidrasi, ketidakseimbangan elektrolit, serta malnutrisi. Penurunan berat badan ditemukan pada 65% pasien dengan GOO. Laporan Kasus Tn. B, 62 tahun, dengan diagnosis tumor ganas kolon asenden, pasca laparotomi hemikolektomi dekstra, eksklusi pilorus, dan gastrojejunostomi. Sejak satu tahun sebelum masuk rumah sakit, pasien mengeluhkan mual dan muntah disertai nyeri perut hilang timbul, terutama sebelah kanan. Pada pemeriksaan didapatkan tumor pada usus besar dan dilakukan operasi hemikolektomi kanan. Saat pembedahan, terdapat perlengketan tumor pada duodenum dan saat dibebaskan terjadi cedera pada duodenum, sehingga dilakukan eksklusi pilorus serta gastrojejunostomi. Sembilan hari pasca pembedahan dilakukan relaparotomi gastrojejunostomi Roux-en-Y serta adhesiolisis akibat adanya stenosis dan adhesi. Pasien mengalami penurunan berat badan sebanyak 19 kg dalam waktu 1 tahun terakhir. Terapi nutrisi berupa diet 1420 kkal, protein 1.1g/kgBB/hari, lemak 32%, dan karbohidrat 50% dalam bentuk nutrisi parenteral. Pemberian mikronutrien enteral untuk sementara ditunda. Pemantauan dilakukan setiap hari pada pasien berupa toleransi asupan, saluran cerna, tanda vital serta keseimbangan cairan.  Kesimpulan Stenosis gastrojejunostomi merupakan komplikasi yang jarang terjadi, namun dapat mengakibatkan terjadinya GOO. Pemberian nutrisi parenteral perioperasi diberikan pada pasien yang tidak dapat mencukupi kebutuhan energi melalui oral atau enteral, serta kondisi malnutrisi berat pada pasien yang akan menjalani pembedahan. Nasogastrojejunal tube merupakan jalur pilihan pemberian nutrisi yang diutamakan pada GOO. Perhimpunan Dokter Gizi Klinik Indonesia 2021-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/59 10.54773/ijcnp.v4i1.59 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 4 No. 1 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 24-35 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 4 No 1 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 24-35 2775-5215 2597-4297 10.54773/ijcnp.v4i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/59/41

oai:ojs2.journal-ijcnp.com:article/63 2022-12-02T15:56:01Z IJCNP:RA

HUBUNGAN KONTROL GLIKEMIK PREOPERATIF DAN GANGGUAN GINJAL AKUT PASCA CORONARY ARTERIAL BYPASS GRAFTING PADA PASIEN DIABETES MELLITUS Rayhan, Muhammad Joe, Juweni Latar Belakang: Diabetes mellitus (DM) dan kontrol glikemik telah diajukan sebagai salah satu faktor risiko gangguan ginjal akut (GGA) pasca coronary arterial bypass grafting (CABG) walaupun dengan bukti yang terbatas, sehingga hubungan kedua penyakit perlu diteliti lebih lanjutTujuan: Tujuan penelitian ini adalah memberikan bukti lebih lanjut terkait pengaruh DM dan kontrol glikemik terhadap insidensi GGA pasca CABG. Metodologi: Suatu penelitian dengan desain cross sectional dilaksanakan di unit perawatan intensif bedah dewasa National Cardiovascular Center Harapan Kita, Jakarta, Indonesia. Populasi penelitian ini mencakup 84 subjek dengan metode sampling konsekutif. Kontrol glikemik pasien DM diklasifikasikan berdasarkan target nilai HbA1c pada panduan American Diabetes Association 2018. Analisis secara bivariat dilakukan untuk melihat hubungan antara berbagai faktor dan insidensi GGA. Berbagai faktor disesuaikan dengan analisis multivariat untuk menilai peran DM dan kontrol glikemik sebagai faktor independen. Hasil: Rerata usia dan tekanan darah sistolik berbeda secara signifikan antar kelompok dengan rerata usia tertinggi pada kelompok DM terkontrol dan tekanan darah tertinggi pada kelompok DM tidak terkontrol. Karakteristik demografis dan berbagai faktor selain DM tidak menunjukan hubungan yang signifikan dengan insidensi GGA. Analisis multivariat menunjukan bahwa pada kelompok DM dengan HbA1c terkontrol, insidensi GGA lebih rendah secara signifikan (OR 0.13, IK 95%, 0.13 - 0.24) dibandingkan dengan kelompok lainnya. Rasio odd GGA lebih tinggi pada kelompok DM tidak terkontrol, tetapi tidak terbukti signifikan secara statistik (OR 1.03, IK 95%, 0.158 - 6.69). Simpulan: Penelitian ini memberikan bukti pentingnya kontrol glikemik pra-operasi dalam mencegah terjadinya GGA pasca CABG pada pasien diabetes. Perhimpunan Dokter Gizi Klinik Indonesia 2021-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/63 10.54773/ijcnp.v4i1.63 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 4 No. 1 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 63-73 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 4 No 1 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 63-73 2775-5215 2597-4297 10.54773/ijcnp.v4i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/63/49

oai:ojs2.journal-ijcnp.com:article/64 2022-12-02T15:56:00Z IJCNP:RA

HUBUNGAN ANTARA KENAIKAN BERAT BADAN SELAMA KEHAMILAN DENGAN KEJADIAN KETUBAN PECAH DINI DI KABUPATEN WAJO Alfitra Salam Nadyah Fhirastika Annisha Helvian Background : Nutritional status could be used as an assessment of the risk of premature rupture of membranes. One way to determine the nutritional status of pregnant women is to calculate the gestational weight gain of women based on body mass index before pregnancy. Objective : The purpose of this study was to determine the relationship between gestational weight gain and the occurrences of premature rupture of membranes. Methodology : An observational analytic study with a cross sectional approach was adopted in this study. The data of this study were collected from the patients’ medical records at RSUD Lamaddukelleng of Wajo Regency in which the inclusion and exclusion sampling criteria were used. A total of 90 samples of patients’ medical record was obtained related to premature rupture of membranes. The collected data were processed and analyzed using the Chi-Square test with the p value of <0.05. Result : The results of the study indicated that there was a significant relationship between weight gain during pregnancy and the occurrence of premature rupture of membranes with the p value of 0.016. Conclusion : This study concluded that while there is a significant relationship between weight gain during pregnancy and premature rupture of membranes Perhimpunan Dokter Gizi Klinik Indonesia 2021-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/64 10.54773/ijcnp.v4i1.64 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 4 No. 1 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 74-81 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 4 No 1 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 74-81 2775-5215 2597-4297 10.54773/ijcnp.v4i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/64/51

oai:ojs2.journal-ijcnp.com:article/67 2022-12-02T15:56:00Z IJCNP:RA

THE EFFECT OF OLIVE OIL SUPPLEMENTATION IN ADOLESENCE Andi Faradilah Darmawansyih Darwis, Burhanuddin Background Olive oil has been shown to reduce the risk of atherosclerosis through its anti-inflammatory, antioxidant, and vasodilator effects. Olive oil contains polyphenols against the reaction of Reactive Oxygen Species. In Al Quran, Surah Al Mu'minin verse 20, it is stated that olive oil can be helpful as an appetite enhancer. This effect can occur through the role of MUFA as olive oil composition in the mechanism of the gut-brain axis where the hormone ghrelin produced by the intestine will enter the brain to induce appetite. The Adolescent period is a significant concern because this is a period of growth and development that requires adequate nutritional intake. The sustainability of appetite in adolescents is a good sign for fulfilling nutritional needs to support optimal growth and development. Objective This study aims to examine the effect of olive oil supplementation on the appetite score in adolescents. Methods The study was conducted at the Tahfizh Al Quran Zam-Zam Islamic Boarding School with 30 subjects divided into two groups: the treatment group (n = 15) and the control group (n = 15) who met the inclusion criteria. The study revealed that no difference was showed in the proportion of appetite scores in the two groups. Conclusion There is no difference of the appetite scores on the administration of olive oil in adolescents. Key words: Olive oil, food intake, appetite score, adolescents.       Perhimpunan Dokter Gizi Klinik Indonesia 2021-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/67 10.54773/ijcnp.v4i1.67 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 4 No. 1 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 55-62 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 4 No 1 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 55-62 2775-5215 2597-4297 10.54773/ijcnp.v4i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/67/52

oai:ojs2.journal-ijcnp.com:article/72 2022-12-02T15:56:00Z IJCNP:CR

PERBANDINGAN BERAS RAGI MERAH DAN SIMVASTATIN DALAM MENURUNKAN PROFIL LIPID : EVIDENCE-BASED CASE REPORT Dian Sarah Mutiara, Dian Sarah Mutiara Diana Sunardi Abstract Background: Dyslipidemia is major risk factor of non-communicable disease and nutraceutical like red yeast rice (RYR) may be helpful as alternative to lowering lipid profile in dyslipidemia. Research objectives: This literature is to critically analyze the comparison RYR and simvastatin in lowering lipid profile. Methods: A search for relevant literatures in PubMed, Scopus, Cochrane, and Science Direct was conducted. We assessing the relevancy and eligibility of the literatures. Three literatures were selected and critically appraised. Results: There were no significant different between RYR and statin group for triglyceride (TG), high-density lipoprotein-cholesterol (HDL-C), especially the total cholesterol (TC)  and the low-density lipoprotein-cholesterol (LDL-C) level. Red yeast rice (RYR) show less fatigue side effect than statin. Conclusions: Nutraceutical like RYR can be an alternative to lowering lipid profile especially TC level and LDL-C level and solution for patients who experience statin-associated myalgia. Keywords: red yeast rice, monacolin K, simvastatin, lipid profile Perhimpunan Dokter Gizi Klinik Indonesia 2021-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/72 10.54773/ijcnp.v4i2.72 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 4 No. 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 127-138 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 4 No 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 127-138 2775-5215 2597-4297 10.54773/ijcnp.v4i2 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/72/59

oai:ojs2.journal-ijcnp.com:article/73 2022-12-02T15:55:59Z IJCNP:CR

TERAPI NUTRISI PADA KARSINOMA AMELOBLASTIK DENGAN KEMOTERAPI Rabiah, Rabiah Bukhari, Agussalim Kesumasari, Citra Safitri, Asrini Karsinoma ameloblastik adalah tumor ganas epitel odontogenik yang sangat jarang terjadi, terhitung sekitar 2% dari tumor odontogenik. Tujuan utama terapi nutrisi pada penderita kanker adalah untuk mempertahankan atau meningkatkan status gizi sehingga dapat memperkecil terjadinya komplikasi, meningkatkan efektivitas terapi kanker (bedah, kemoterapi, radiasi), kualitas hidup dan survival penderita. Pria usia 59 tahun dikonsulkan dengan diagnosis karsinoma ameloblastik dan malnutrisi berat (Subjective Global Assesment Skor C). Pasien memiliki riwayat asupan yang kurang dan perubahan konsistensi asupan selama 4 bulan dan memberat 10 hari terakhir karena disfagia. Terapi nutrisi pre-kemoterapi  diberikan dengan target 1900 kkal secara bertahap melalui enteral dan parenteral dengan protein 1,5 gram/kgBB ideal/hari. Pada akhir masa perawatan terdapat perbaikan metabolik seperti deplesi system imun,albumin dan balance nitrogen. Penanganan nutrisi perlu dilakukan pada pasien kanker yang akan menjalani kemoterapi untuk optimalisasi kondisi pre-kemoterapi dan memperbaiki klinis dan metabolik pasien post-kemoterapi. Perhimpunan Dokter Gizi Klinik Indonesia 2021-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/73 10.54773/ijcnp.v4i2.73 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 4 No. 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 102-111 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 4 No 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 102-111 2775-5215 2597-4297 10.54773/ijcnp.v4i2 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/73/55

oai:ojs2.journal-ijcnp.com:article/74 2022-12-02T15:55:59Z IJCNP:CR

EFFECT OF MATERNAL VITAMIN D SUPPLEMENTATION DURING LACTATION EFFECT ON INFANTS' PROPENSITY TO INFECTION : AN EVIDENCE-BASED CASE REPORT Kosasih, Raphael Sunardi, Diana Abstract Introduction: Vitamin D deficiency has become more prevalent around the world along with a sedentary lifestyle and limited exposure to sunlight. Deficiencies of vitamin D in lactating mothers could cause deficiencies in their infants and vitamin D deficient infants are at higher risk of having infectious diseases. Supplementation of Vitamin D to lactating mothers may benefit both mothers and infants to reduce infection morbidity. Methods: Relevant literature research was conducted in PubMed, Cochrane, and SciELO using relevant keywords and advanced search methods. Relevant literature was then screened for duplication, relevance, and eligibility. Results: A randomized-controlled trial was selected. The study showed that supplementation of 3000µg oral vitamin D3 to lactating mothers significantly raise their infants' serum vitamin D (p<0.01) and reduce infection morbidity (p<0.01) Conclusions: Oral supplementation of vitamin D3 could be given to lactating mothers to improve their infants' serum vitamin D and reduce infection morbidity. Keywords: vitamin D, lactation, infants' infection Perhimpunan Dokter Gizi Klinik Indonesia 2021-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://journal-ijcnp.com/index.php/IJCNP/article/view/74 10.54773/ijcnp.v4i2.74 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 4 No. 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 112-117 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 4 No 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 112-117 2775-5215 2597-4297 10.54773/ijcnp.v4i2

oai:ojs2.journal-ijcnp.com:article/75 2022-12-02T15:55:58Z IJCNP:RA

PENGELOLAAN GIZI BENCANA PADA IBU HAMIL DAN IBU MENYUSUI Rachman, Nita Nurul Diyah Eka Andayani Indonesia merupakan negara kepulauan yang luas dan mempunyai potensi kejadian bencana yang tinggi. Masalah kesehatan yaitu malnutrisi merupakan salah satu masalah utama dalam kondisi bencana .Rusaknya berbagai sarana dan prasarana pelayanan umum dan kesehatan, terputusnya jalur distribusi pangan dan ketersediaan  pangan yang terbatas, sanitasi lingkungan yang buruk dan rusaknya sarana air bersih menjadi dasar terjadinya kekurangan asupan nutrisi pada korban terdampak bencana. Pandemik COVID-19 yang saat ini terjadi tentunya menjadi tantangan tersendiri bagi dunia kesehatan.  Diperlukan perhatian khusus untuk pengelolaan gizi pada saat bencana, terutama pada ibu hamil dan ibu menyusui sebagai populasi rentan. Pengelolaan gizi tidak hanya berkaitan dengan permasalahan kesehatan pada ibu hamil dan ibu menyusui saja, tetapi menjadi kesatuan dengan dampak kesehatan yang akan terjadi pada masa depan kesehatan bayi yang akan dilahirkan. Pengetahuan akan pengelolaan gizi yang baik diharapkan dapat menurunkan angka kejadian masalah kesehatan yang terjadi pada saat bencana Perhimpunan Dokter Gizi Klinik Indonesia 2021-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/75 10.54773/ijcnp.v4i2.75 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 4 No. 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 148-164 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 4 No 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 148-164 2775-5215 2597-4297 10.54773/ijcnp.v4i2 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/75/60

oai:ojs2.journal-ijcnp.com:article/76 2022-12-02T15:55:58Z IJCNP:RA

HUBUNGAN ANTARA ANGKA KECUKUPAN ENERGI DAN PROTEIN DENGAN KESEMBUHAN LUKA PADA PASIEN ULKUS DEKUBITUS Safitri, Nathalia Hertanto Wahyu Subagio Etisa Adi Murbawani Niken Puruhita Amalia Sukmadianti ABSTRAK  Latar belakang : Ulkus dekubitus merupakan masalah kesehatan di banyak negara dan malnutrisi merupakan salah satu faktor yang berpengaruh dalam perkembangan ulkus dekubitus, namun investigasi klinis masih jarang dilakukan untuk mengamati kebutuhan jumlah energi dan protein pada kesembuhan luka. Tujuan penelitian : Menganalisis hubungan antara angka kecukupan energi dan protein dengan kesembuhan luka pada pasien ulkus dekubitus. Menganalisis hubungan antara angka kecukupan energi dan protein dengan kesembuhan luka pada pasien ulkus dekubitus dikontrol dengan faktor usia, indeks massa tubuh, dan adanya infeksi. Metode penelitian : Studi observasional dengan pendekatan cross sectional melibatkan 40 subjek sesuai kriteria inklusi dan eksklusi. Kesembuhan luka dinilai menggunakan PUSH score tools 3.0, angka kecukupan energi dan angka kecukupan protein dinilai berdasarkan rata-rata asupan total masing-masing yang diberikan dalam seminggu. Hasil : Terdapat hubungan lemah antara angka kecukupan energi dengan kesembuhan luka (r= 0,37 dan p= 0,02). Adanya hubungan sedang antara angka kecukupan protein dengan kesembuhan luka (r= 0,42 dan p= 0,01). Simpulan : Terdapat hubungan bermakna antara angka kecukupan energi dan protein dengan kesembuhan luka pada pasien ulkus dekubitus. Faktor usia, indeks massa tubuh, dan infeksi pada ulkus dekubitus bukan merupakan variabel perancu dalam penelitian ini. Kata kunci : Angka kecukupan energi, angka kecukupan protein, kesembuhan luka, ulkus dekubitus. Perhimpunan Dokter Gizi Klinik Indonesia 2021-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/76 10.54773/ijcnp.v4i2.76 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 4 No. 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 165-177 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 4 No 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 165-177 2775-5215 2597-4297 10.54773/ijcnp.v4i2 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/76/61

oai:ojs2.journal-ijcnp.com:article/78 2022-12-02T15:55:57Z IJCNP:RA

HUBUNGAN DIAMETER SAGITAL ABDOMEN DENGAN HbA1c PADA PASIEN LAKI-LAKI DENGAN OVERWEIGHT/OBESITAS Ardinasari, Eiyta Niken Puruhita Etisa Adi Murbawani Siti Fatimah Muis Amalia Sukmadianti Latar belakang: Obesitas sentral menjadi faktor risiko terjadinya DM tipe 2 dan sindrom metabolik. Pengukuran menggunakan diameter sagital abdomen dapat digunakan sebagai penanda pengganti untuk memprediksi risiko DM tipe 2. Referensi penggunaan diameter sagital abdomen sebagai alat antropometri untuk penapisan risiko DM tipe 2  di Indonesia masih terbatas. Tujuan : Menganalisis hubungan antara diameter sagital abdominal dengan kadar HbA1c Metode penelitian : Penelitian ini adalah penelitian observasional dengan pendekatan cross sectional. Sebanyak 60 subyek berusia antara 40-55 tahun yang berada di wilayah kerja kota Semarang yang overweight/ obese dipilih sebagai subjek setelah sebelumnya menyetujui informed consent dan penelitian mendapatkan persetujuan Etik. Instrumen penelitian adalah kaliper diameter sagital abdomen, pita ukur, dan Chemistry analyzer HbA1c. Penghitungan data menggunakan uji korelasi Spearman dan regresi linier. Hasil : Diameter sagital abdomen berbanding lurus dengan kadar HbA1c pada subyek laki-laki overweight/ obese (p < 0,001, r= 0,490). Kenaikan 1 cm SAD meningkatkan kadar HbA1c  sebesar 17%. Dibutuhkan penelitian lebih lanjut untuk memperkuat penemuan ini pada subjek dengan variabilitas yang lebih beragam. Simpulan : Diameter sagital abdomen dapat dijadikan alat skrining antropometri pengganti untuk penapisan risiko DM tipe 2 pada orang dengan overweight/obese.   Kata kunci : Diameter sagital abdomen, DM tipe 2, HbA1c, obesitas sentral Perhimpunan Dokter Gizi Klinik Indonesia 2021-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/78 10.54773/ijcnp.v4i2.78 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 4 No. 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 189-203 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 4 No 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 189-203 2775-5215 2597-4297 10.54773/ijcnp.v4i2 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/78/63

oai:ojs2.journal-ijcnp.com:article/79 2022-12-02T15:55:57Z IJCNP:CR

EFFECTS OF PROBIOTICS ON LIPID PROFILES IN HYPERCHOLESTEROLEMIA ADULT PATIENTS: AN EVIDENCE-BASED CASE REPORT Elisa Lestari, Wiji Background: Hypercholesterolemia prevalence was 39% in adults and a risk factor for cardiovascular, cerebrovascular, atherosclerotic disease, leading to vertigo. Diet and specific food potentiate in dyslipidemia risk reduction. Several studies have been proposed that probiotics have a hypocholesterolemic effect. Objectives: This study aims to determine the effect of probiotics on lipid profiles in hypercholesterolemia adult patients. Methods: Electronic literature searching was conducted from Pubmed, Scopus, and Cochrane Library. MeSH Terms combined with Title/Abstract are used in advanced search based on inclusion and exclusion criteria. Results: Critical appraisal was conducted for a systematic review and meta-analysis of randomized controlled trials. Probiotic supplementation significantly decreases total cholesterol and low-density lipoprotein cholesterol levels but not statistically significant in high-density lipoprotein and triglycerides levels. Conclusion: Single strain Lactobacillus plantarum probiotics for at least six weeks can improve total cholesterol levels in hypercholesterolemia adult patients. Perhimpunan Dokter Gizi Klinik Indonesia 2021-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/79 10.54773/ijcnp.v4i2.79 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 4 No. 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 118-126 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 4 No 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 118-126 2775-5215 2597-4297 10.54773/ijcnp.v4i2 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/79/58

oai:ojs2.journal-ijcnp.com:article/82 2022-12-02T15:55:56Z IJCNP:CR

EFFICACY OF IMMUNONUTRITION CONTAINING OMEGA-3 FATTY ACIDS TO REDUCE MORTALITY IN ACUTE RESPIRATORY DISTRESS SYNDROME: AN EVIDENCED-BASED CASE REPORT Nita Wiji Lestari Background: Acute respiratory distress syndrome (ARDS) remains one among the most reasons for ICU admission. It is related to high rates of mortality despite many recent advances in overall support. A relative increase in oxidative stress in patients with ARDS results in increased alveolar injury. Immunonutrion containing omega 3 fatty acids is one among the strategies that currently receiving attention within the management of ARDS since they are known to have anti-inflammatory effects, but the results are still inconsistent. Objective: This study aimed to find out the efficacy of immunonutrition containing omega 3 fatty acids in reducing mortality in patients with ARDS. Methodology: Electronic literature researches were performed in PubMed, Cochrane, and Scopus. MeSH term and title/abstracts were screened based on inclusion and exclusion criteria before relevant journals were reviewed. Results: Two articles were selected based on the eligibility criteria and relevance to the clinical questions. The study of Langlois P. et al. found significantly reduced mortality in patients receiving continuous enteral infusion route of immunonutrition containing omega 3 fatty acids. While Dushianthan A. et al. found little or no mortality benefit with the administration of immunonutrition containing omega 3 fatty acids. Conclusions: There is little or no mortality reduction within the administration of immunonutrition containing omega 3 fatty acids. Keywords: acute respiratory distress syndrome, ARDS, immunonutrition, omega 3 fatty acids, mortality. Perhimpunan Dokter Gizi Klinik Indonesia 2022-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/82 10.54773/ijcnp.v5i1.82 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 12-20 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 12-20 2775-5215 2597-4297 10.54773/ijcnp.v5i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/82/65

oai:ojs2.journal-ijcnp.com:article/83 2022-12-02T15:55:57Z IJCNP:RA

PERBEDAAN PROFIL LIPID TIKUS RATTUS NORVEGICUS PADA PEMBERIAN DIET KETOGENIK LEMAK JENUH DAN LEMAK TIDAK JENUH SELAMA EMPAT MINGGU Liona Dewi, Dewa Ayu Muliono , Ari Christy Waworuntu, Gladdy Lysias Ongkodjojo, Evelyn Latar Belakang. Diet ketogenik merupakan diet populer untuk menurunkan berat badan dengan efek terhadap profil lipid masih inkonsisten. Tujuan Penelitian. Menganalisis perbedaan profil lipid tikus Rattus norvegicus pada pemberian pakan ketogenik dengan komposisi  lemak 80% (jenuh dan tidak jenuh), protein 15% dan karbohidrat 5%  selama 4 minggu. Metodologi. Desain penelitian true experimental dengan posttest only control group design. Tikus jantan dengan berat badan 125-150 g  dibagi secara random dalam 3 kelompok (P0, P1 dan P2) menerima diet 25-30 kkal/hari sesuai dengan kebutuhan energi harian tikus. P0 kelompok kontrol menerima pakan tikus biasa. P1 menerima diet ketogenik lemak jenuh dari margarin. P2 menerima diet ketogenik lemak tak jenuh dari minyak zaitun ekstra virgin. Kolesterol total, LDL, HDL dan trigliserida diperiksa pada minggu ke 2 dan 4. Data dianalisis dengan Uji t Independen dan Mann Whitney (p<0,05). Hasil. Pada P1 terdapat perbedaan kadar HDL yang signifikan (38 menjadi 22,40 mg/dL, p=0,005) namun perbedaan kadar kolesterol total, LDL dan kadar trigliserida tidak signifikan. Pada P2 didapatkan perbedaan yang signifikan pada kadar kolesterol total (93,20 menjadi 67,80 mg/dL, p=0,042), HDL (29,40 menjadi 22,20 mg/dL, p=0,004), LDL (25,60 menjadi 13,80 mg/dL, p=0,009), dan trigliserida (100,80 menjadi 51,40 mg/dL, p=0,016). Pada P0 tidak ada perbedaan yang signifikan. Kesimpulan. Diet ketogenik dengan lemak tidak jenuh selama 4 minggu  menunjukkan efek yang menguntungkan dalam menurunkan kadar kolesterol total, LDL dan trigliserida pada tikus Rattus norvegicus. kata kunci: diet ketogenik, lemak jenuh, lemak tidak jenuh, kolesterol total, HDL, LDL, trigliserida Perhimpunan Dokter Gizi Klinik Indonesia 2021-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/83 10.54773/ijcnp.v4i2.83 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 4 No. 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 178-188 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 4 No 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 178-188 2775-5215 2597-4297 10.54773/ijcnp.v4i2 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/83/62

oai:ojs2.journal-ijcnp.com:article/84 2022-12-02T15:55:52Z IJCNP:RA

KECEPATAN PENCAPAIAN TARGET ENERGI DAN PROTEIN SERTA HUBUNGANNYA DENGAN PENURUNAN INDEKS MASSA TUBUH DAN LINGKAR LENGAN ATAS PADA PASIEN STROKE Ramadhan, Joriandhita Hertanto Wahyu Subagio Enny Probosari Background: Some anthropometrics assessment on risk of malnutrition are by measuring the mid-arm circumference (MAC) and calculating the body mass index (BMI). Objective: To analyze the relationship between days of energy and protein target achievement to the reduction of MAC and BMI in stroke patients in Indonesia. Method: The study design was an observational study with a cross-sectional approach to determine the relationship between days of energy and protein target achievement to the reduction of MAC and BMI. A total of 55 subjects who met the inclusion and exclusion criteria were taken at the Stroke Unit of RSUP Dr. Kariadi Semarang during January-March 2021. MAC measurements and BMI calculations were carried out. Analysis of the relationship between dependent and independent variables using the chi square statistical test. Results: Most of the subjects achieved their energy and protein targets within ≤ 3 days. Days of energy and protein target achievement did not correlate with the reduction in MAC and BMI statistically (p> 0.05), but the research data stated that as a percentage, one third of the subjects who reached the energy and protein targets ≤ 3 days did not experience reduction. Conclusion: All subjects were stroke patients aged 19-59 years where 49 (89,1%) could meet their energy and protein targets within ≤ 3 days and 17 (34,7%) subjects did not experience reduction in MAC and BMI.   Keywords: Stroke, MAC, BMI, malnutrition, anthropometry   Perhimpunan Dokter Gizi Klinik Indonesia 2022-06-24 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/84 10.54773/ijcnp.v5i1.84 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 94-101 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 94-101 2775-5215 2597-4297 10.54773/ijcnp.v5i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/84/73

oai:ojs2.journal-ijcnp.com:article/85 2022-12-02T15:55:55Z IJCNP:RA

FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN DIARE DI UNIT STROKE RSUP DR. KARIADI: diare Hilmansyah, Taufik Hertanto Wahyu Subagio Annta Kern Abstrak Latar belakang: Diare disebabkan oleh multifaktorial dan beberapa faktor diketahui berhubungan dengan diare selama pasien dirawat yaitu usia lanjut, lama rawat inap, kejadian infeksi, penggunaan antibiotik, dan status gizi malnutrisi. Di RSUP Dr. Kariadi Semarang belum pernah dilakukan penelitian faktor yang berhubungan dengan diare. Tujuan: Menghitung besar risiko usia lanjut, lama rawat inap, kejadian infeksi, penggunaan antibiotik, formula nutrisi enteral non pabrikasi, dan status gizi malnutrisi dengan kejadian diare. Metoda: Jenis penelitian case control dengan mengambil data restrospektif pasien stroke yang memenuhi kriteria inklusi dan eksklusi selama Januari – April 2020. Dilakukan pemeriksaan data berdasarkan variabel bebas, dilakukan pencatatan dan dianalisis hubungan dengan menggunakan uji statistik Chi Square. Hasil: Sebanyak 40 subyek penelitian yang di rawat di unit stroke RSUP Dr Kariadi mayoritas diagnosis stroke non hemoragik (55%) dan laki-laki (60%). Mayoritas subyek usia non geriatri yaitu kurang dari 60 tahun. Hasil penelitian menunjukkan adanya hubungan yang signifikan pada faktor usia lanjut, lama rawat inap dan penggunaan antibiotik terhadap diare. Usia lanjut subyek (p = 0,043) dengan risiko 10 kali lipat. Lama rawat inap > 5 hari (p = 0,031) dengan risiko 11,56 kali lipat. Penggunaan antibiotik dengan risiko 13,5 kali lipat. Sedangkan variabel lain tidak signifikan. Simpulan: Terdapat hubungan usia lanjut, lama rawat inap >5 hari dan penggunaan antibiotik terhadap kejadian diare pada pasien stroke yang di rawat di unit stroke RSUP Dr Kariadi Kata kunci: diare, unit stroke, geriatri, antibiotik, lama rawat inap Perhimpunan Dokter Gizi Klinik Indonesia 2022-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/85 10.54773/ijcnp.v5i1.85 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 60-68 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 60-68 2775-5215 2597-4297 10.54773/ijcnp.v5i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/85/69

oai:ojs2.journal-ijcnp.com:article/86 2022-12-02T15:56:08Z IJCNP:CR

PEMBERIAN L-ALANYL L-GLUTAMYL DENGAN ASUPAN TINGGI PROTEIN PADA PASIEN LUKA BAKAR LISTRIK 48% DERAJAT II-III Margherita Suppini Sumardi Nurpudji A. Taslim A. Yasmin Syauki Luka bakar merupakan masalah kesehatan masyarakat yang paling sering ditemukan pada usia produktif. Data unit luka bakar rumah sakit di Indonesia menunjukkan terjadinya peningkatan mortalitas. Pada luka bakar berat terjadi hipermetabolisme dan proteolisis yang tinggi sehingga diperlukan terapi nutrisi yang tepat dan dini. Dilaporkan kasus seorang laki-laki, 18 tahun dengan keluhan nafsu makan melalui oral menurun dengan diagnosis severe protein energy malnutrition, luka bakar listrik 48% grade II-III. Terapi nutrisi yang diberikan adalah diet energi 3350 kkal melalui oral dan parenteral dengan komposisi protein: karbohidrat: lemak = 14,3%: 50%: 35,7%. Diet dimulai dengan 40% lalu 80% dan 100% dari total energi (hari ke-III). Kebutuhan protein 2,0 g/kg/hari dengan suplementasi parenteral glutamin (13,46 g/hari). Suplementasi mikronutrien berupa zink 40 mg/24 jam, ekstrak ikan gabus 480 g/hari, vitamin B1 4 mg/8 jam, vitamin C 500 mg/12 jam, vitamin A 10.000 IU/24 jam. Perbaikan balans nitrogen dari -7,7 menjadi +5,36. Albumin dan protein total mengalami perbaikan dari 2, 4 g/dl menjadi 3,5 g/dl dan 6,8 g/dl menjadi 6,8 g/dl. Penyembuhan luka terjadi dengan baik (inflamasi-repair dan remodeling) selama tiga puluh tiga hari masa perawatan. Kesimpulan: suplementasi glutamin dengan asupan tinggi protein dapat mempercepat penyembuhan luka, dan mencegah mortalitas pada pasien luka bakar berat. Perhimpunan Dokter Gizi Klinik Indonesia 2019-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/86 10.54773/ijcnp.v2i1.86 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 2 No. 1 (2019): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 1-10 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 2 No 1 (2019): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 1-10 2775-5215 2597-4297 10.54773/ijcnp.v2i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/86/56

oai:ojs2.journal-ijcnp.com:article/87 2022-12-02T15:56:08Z IJCNP:RA

POTENSI AKTIVITAS ANTIMIKROBA MADU DAN HABBATUSSAUDA TERHADAP BAKTERI ESCHERICHIA COLI SECARA IN VITRO Alifia Ayu Delima Utami Murti Pratiwi Asriani Madu dan habbatussauda memiliki aktivitas antibakteri. Komponen yang terdapat di dalam madu antara lain keasaman, tekanan osmotik, dan hidrogen peroksida, asam aromatik serta omponen fenol juga berperan dalam aktivitas antibakteri. Sedangkan habbatussauda sendiri tannin, tymoquinon, thymol, a-pinene, p-cymene dengan cara menghambat pembentukan asam nukleat (RNA) dan sintesis protein yang berperan sebagai antibakteri dan antioksidan pada proses infeksi. Tujuan dari penelitian ini untuk mengetahui potensi antibakteri madu dan Habbatussauda terhadap bakteri Escherichia coli. Jenis penelitian ini adalah eksperimental dengan metode Post Test Only Control Group Design yang dilakukan secara in vitro. Hasil dari penelitian in vitro menunjukan bahwa terdapat pengaruh pemberian perlakuan madu, habbatussaudah dan kombinasi terhadap daya hambat pertumbuhan e-coli (<0.05). Perhimpunan Dokter Gizi Klinik Indonesia 2019-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/87 10.54773/ijcnp.v2i1.87 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 2 No. 1 (2019): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 11-19 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 2 No 1 (2019): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) ; 11-19 2775-5215 2597-4297 10.54773/ijcnp.v2i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/87/57

oai:ojs2.journal-ijcnp.com:article/89 2022-12-02T15:55:56Z IJCNP:CR

TERAPI MEDIK GIZI PADA PASIEN SPACE OCCUPYING LESION SEREBELUM METASTASIS DENGAN RISIKO TINGGI SINDROM REFEEDING Dian Sarah Mutiara Diyah Eka Andayani Sunardi, Diana Tiara Aninditha Metastasis otak merupakan keganasan terbanyak pada susunan saraf pusat yang dapat menimbulkan penurunan kesadaran, menurunkan asupan nutrisi, meningkatkan risiko malnutrisi serta terjadinya gangguan elektrolit yang dapat meningkatkan risiko terjadinya sindrom refeeding. Laporan kasus ini bertujuan untuk membahas tatalaksana pasien dalam menjaga status nutrisi dan meningkatkan kualitas hidup pada pasien space occupying lesion (SOL) serebelum metastasis dengan risiko sindrom refeeding. Laporan kasus berasal dari pasien rawat inap yaitu perempuan berusia 54 tahun dengan diagnosis hidrosefalus obstruktif ec SOL serebelum suspek metastasis, karsinoma mammae sinistra stadium III T3N3M1 dengan malnutrisi berat, kaheksia kanker, dan risiko tinggi sindrom refeeding. Pasien mengalami kondisi malnutrisi dan terdapat gangguan elektrolit. Pasien menalami penurunan kesadaran dan membutuhkan jalur nutrisi artifisial. Pasien mendapatkan terapi medik gizi berupa peningkatan nutrisi bertahap dan koreksi elektrolit. Namun, kondisi klinis pasien kurang baik ditandai adanya efusi pleura masif dan perdarahan saluran cerna sehingga pasien dalam kasus tersebut meninggal. Pemberian nutrisi pada pasien dengan risiko sindrom refeeding disesuaikan dengan kondisi klinis, ditingkatkan bertahap, dan mengatasi gangguan elektrolit. kata kunci : kaheksia, kanker, malnutrisi, metastasis, sindrom refeeding Perhimpunan Dokter Gizi Klinik Indonesia 2022-02-25 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/89 10.54773/ijcnp.v5i1.89 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 1-11 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 1-11 2775-5215 2597-4297 10.54773/ijcnp.v5i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/89/64

oai:ojs2.journal-ijcnp.com:article/90 2022-12-02T15:55:55Z IJCNP:CR

TERAPI NUTRISI PADA PASIEN ABSES HEPAR LOBUS SINISTRA DENGAN PLEUROPNEUMONIA DAN SEVERE PROTEIN ENERGY MALNUTRITION Dwi Handayani, Nevi Suryani As’ad Mardiana Majid Asrini Safitri Abses hepar adalah bentuk infeksi pada hati yang disebabkan karena infeksi bakteri, parasit, jamur, yang ditandai dengan adanya proses supurasi dengan pembentukan pus di dalam parenkim hati. Abses hati dapat berdampak buruk pada status gizi melalui asupan makanan yang berkurang, malabsorpsi, peningkatan katabolisme dan penyerapan nutrisi yang diperlukan untuk sintesis dan pertumbuhan jaringan. Wanita usia 73 tahun dikonsulkan dengan diagnosis abses hepar lobus sinistra dan adhesi ileum grade IV dengan Pleuropneumonia dan malnutrisi berat (Subjective Global Assesment Skor C dan Skor MNA 7). Pasien memiliki riwayat asupan yang kurang sejak 3 minggu terakhir karena nyeri perut. Terapi nutrisi diberikan 1200 kkal, ditingkatkan bertahap menjadi 1600 kkal sesuai kemampuan dan kondisi pasien, dengan komposisi protein 1.2-1.5 g/kg BB ideal/hari, karbohidrat 50% dan  lemak 30-34.1 % diikuti dengan suplementasi zinc, Vitamin B kompleks, Vitamin C, Vitamin D, curcuma dan kapsul ekstrak ikan gabus. Terapi nutrisi pada abses hepar dengan pemenuhan makronutrien dan mikronutrien yang memadai dan imunonutrisi sangat penting untuk mencegah perburukan penyakit dan luaran  pada pasien ini membaik. Perhimpunan Dokter Gizi Klinik Indonesia 2022-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/90 10.54773/ijcnp.v5i1.90 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 21-30 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 21-30 2775-5215 2597-4297 10.54773/ijcnp.v5i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/90/66

oai:ojs2.journal-ijcnp.com:article/91 2023-06-22T00:58:42Z IJCNP:CR

TERAPI NUTRISI PADA GAGAL JANTUNG KONGESTIF NYHA FC - II DENGAN SEVERE PROTEIN ENERGY MALNUTRITION Rabiah, Rabiah Mardiana Safitri, Asrini Gagal jantung kongestif adalah sindrom klinis kompleks di mana jantung tidak dapat memompa cukup darah untuk memenuhi kebutuhan tubuh. Gagal jantung merupakan epidemik pada sekitar 1% sampai 2% dari populasi di seluruh dunia. Cachexia dan malnutrisi merupakan komplikasi serius dari berbagai penyakit, salah satunya gagal jantung. Malnutrisi pada pasien gagal jantung, merupakan salah satu prediktor dari mortalitas dan dapat menyebabkan kualitas hidup yang kurang baik. Tujuan utama terapi nutrisi pada penderita gagal jantung kongestif adalah untuk mempertahankan dan meningkatkan status gizi sehingga dapat menurunkan morbiditas dan mortalitas  penderita. Pria usia 77 tahun dikonsulkan dengan diagnosis gagal jantung kongestif NYHA FC-II, Hipertensi dan Atrial Fibrilasi dan malnutrisi berat (Subjective Global Assesment Skor C). Pasien memiliki riwayat asupan yang kurang dan perubahan konsistensi asupan selama 1 tahun dan memberat sejak 1 bulan yang lalu karena sesak nafas. Terapi nutrisi melalui diberikan dengan target 1300 kkal secara bertahap melalui oral dan parenteral dengan protein 1-1,2 gram/kgBB ideal/hari. Suplementasi yang diberikan adalah Zinc, Vitamin B Kompleks, Vitamin A, Vitamin C, Vitamin D dan Curcuma. Pada akhir masa perawatan terdapat perbaikan metabolik seperti deplesi sistem imun, magnesium,albumin,enzim transaminase dan kalium. Perhimpunan Dokter Gizi Klinik Indonesia 2022-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/91 10.54773/ijcnp.v5i2.91 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 114-124 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 114-124 2775-5215 2597-4297 10.54773/ijcnp.v5i2 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/91/76 Copyright (c) 2022 Rabiah Rabiah

oai:ojs2.journal-ijcnp.com:article/92 2023-06-22T00:58:38Z IJCNP:RA

SOCIODEMOGRAPHIC PROFILE, PHYSICAL ACTIVITY, DIETARY PATTERNS, AND NUTRITIONAL STATUS OF VEGETARIANS Dewi, Apriyani Supia Kurniati, Ardesy Melizah Dalilah, Dalilah Vegetarianism is one of the most popular dietary patterns in the world, and Indonesians are as well. This study was conducted to determine the profile of vegetarians in Palembang based on socio-demographic characteristics, physical activity level, dietary type, total energy intake, total macronutrient intake, and nutritional status. This study is a descriptive observational study with a cross-sectional design. Maha Vihara Maitreya Duta (MVMD) was the vegetarian population in this survey. Participants who agreed to take part in the survey were at least 18 years old, have been vegetarian for at least three years, were not pregnant or planning to become pregnant, and did not have any chronic ailments. A total of 148 samples were acquired using a consecutive sampling technique. To establish nutritional status, Primary data were collected by completing food recall interviews during the last 24 hours on two non-consecutive days. and measuring height and weight to determine nutritional status. The highest age range of participants was 30–49 years (54,1%). The majority of the population was female (61,5%) and had a college degree (56,1%). Most participants work (85,8%), engage in light-to-moderate physical activity, and have a normal body mass index range (68,2%). Most ate lacto-ovo-vegetarian (59,5%). Most participants were vegetarian for 6-10 years (31,1%). Most motivations for becoming a vegetarian are health-related (45,3%). Vegans consumed more calories, carbs, and protein than non-vegans, but less fat. Most vegan and non-vegan respondents had good nutritional status and were in the sufficient category for achieving calorie and macronutrient requirements. Perhimpunan Dokter Gizi Klinik Indonesia 2022-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/92 10.54773/ijcnp.v5i2.92 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 175-184 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 175-184 2775-5215 2597-4297 10.54773/ijcnp.v5i2 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/92/80 Copyright (c) 2022 Apriyani Supia Dewi, Ardesy Melizah Kurniati, Dalilah Dalilah

oai:ojs2.journal-ijcnp.com:article/93 2022-12-02T15:55:55Z IJCNP:CR

TERAPI GIZI PADA LAKI – LAKI, 70 TAHUN DENGAN ABSES HEPAR, BRONKOPNEUMONIA, REFEEDING SYNDROME, MALNUTRISI BERAT, SARKOPENIA, FRAILTY, DAN SINDROMA GERIATRI Surya Rini, Felita Febe Christianto Annta Kern Nugrohowati Latar Belakang: Prevalensi abses hepar di dunia mencapai 2,3 kasus per 100.000 penduduk.  Keluhan mual, muntah, anoreksia, dan nyeri perut yang merupakan keluhan utama abses hepar tentunya akan menurunkan asupan pasien. Pasien abses hepar sering datang dengan riwayat starvasi lama sehingga berisiko refeeding syndrome Pengobatan abses hepar adalah drainase secara operasi sehingga terapi nutrisi perioperatif menjadi salah satu kunci keberhasilan terapi multidisiplin.   Laporan Kasus: Tn B, 70 tahun, datang dengan keluhan mual, dan muntah setiap kali makan sejak 1 bulan SMRS disertai nyeri perut kanan atas, demam, dan menggigil. Pasien juga mengeluhkan penurunan berat badan dan starvasi sejak 1 bulan. Pemeriksaan fisik abdomen terdapat nyeri tekan kuadran kanan atas (+).  Sebelum diberikan terapi nutrisi, pasien mengalami refeeding syndrome akibat overfeeding yang ditandai dengan deplesi kalium dan magnesium progresif. Pasien diberikan diet mulai dari 10 kkal/kgBB/hari dan untuk terapi refeeding diberikan suplementasi tiamin dan B kompleks serta koreksi MgSO4 dan KCl. Diet mencapai target pada hari ke-5 perawatan. Pasien dilakukan tindakan laparoskopi drainase abses sesuai prosedur ERAS. Pada masa pemulihan pasca operasi, pasien diberikan suplementasi vitamin A, vitamin C, dan zinc. Pasien juga diberikan ONS yang mengandung vitamin A, vitamin E, tembaga dan selenium, omega 3, dan branched chain amino acids. Kesimpulan: Keberhasilan terapi gizi pada pasien ini tampak dari pasien dapat segera ditatalaksana untuk mencegah kondisi fatal akibat refeeding, terjadi peningkatan asupan, berat badan, peningkatan kekuatan genggaman, dan tidak terjadi wound dehiscence selama perawatan di rumah sakit.   Kata kunci: abses hepar, refeeding syndrome, sarkopenia, terapi nutrisi Perhimpunan Dokter Gizi Klinik Indonesia 2022-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/93 10.54773/ijcnp.v5i1.93 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 31-46 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 31-46 2775-5215 2597-4297 10.54773/ijcnp.v5i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/93/67

oai:ojs2.journal-ijcnp.com:article/94 2022-12-02T15:55:54Z IJCNP:RA

PENGARUH PEMBERIAN TEH ROSELA UNGU (HIBISCUS SABDARIFFA LINN) TERHADAP PROFIL LIPID PADA TIKUS HIPERKOLESTEROLEMI Probosari, Enny Etisa Adi Murbawani Aryu Candra Martha Ardiaria Latar Belakang : Dislipidemia merupakan faktor risiko terjadinya penyakit kardiovaskular yang menjadi salah satu penyebab utama kematian di dunia. Bunga rosela sebagai tanaman herbal yang popular di masyarakat Indonesia mengandung bahan aktif yang dapat memperbaiki profil lipid. Tujuan Penelitian: Penelitian ini bertujuan mengetahui pengaruh pemberian seduhan kelopak rosela terhadap profil lipid tikus wistar yang diberi pakan tinggi lemak. Metode : Penelitian ini adalah penelitian eksperimental laboratorium dengan design pre-post test dengan kelompok kontrol, menggunakan 24 ekor tikus wistar jantan usia 3 bulan, dibagi menjadi 4 kelompok yaitu kelompok kontrol diberi pakan standar dan minum ad libitum, kelompok perlakuan P1 diberi pakan standar dan seduhan rosela dosis 1340 mg/KgBB/hari, kelompok perlakuan P2 diberi pakan standar dan seduhan rosela dosis 2700 mg/KgBB/hari, kelompok perlakuan P3 diberi pakan standar dan seduhan rosela dosis 4020 mg/KgBB/ hari selama 30 hari. Pada awal dan akhir perlakuan diambil serum darah untuk mengetahui kadar trigliserida, kolesterol total, HDL, dan LDL. Hasil: Pemberian rosela pada ketiga kelompok perlakuan mengalami penurunan kadar trigliserid, kadar LDL, Peningkatan kadar kolesterol, dan kadar HDL secara bervariasi. Kelompok P3 menunjukan penurunan kadar trigliserid sebesar -61,00±45,41 (p<0,05) lebih baik dibanding kelompok lain. Kelompok P2 menunjukan peningkatan kadar HDL sebesar 10,20±9,89 (p>0,05) lebih baik dibanding kelompok lain. Kelompok P2 menunjukan penurunan LDL sebesar -5,50±7,06   (p>0,05) dibanding kelompok lain. Kesimpulan: Pemberian teh rosela dengan dosis 4020 mg/KgBB/hari selama 30 hari mampu menurunkan kadar trigliserida secara signifikan (p<0,05) pada tikus hiperkolesterolemi.   Kata Kunci : Profil lipid, Rosela, Tikus Wistar Perhimpunan Dokter Gizi Klinik Indonesia 2022-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/94 10.54773/ijcnp.v5i1.94 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 69-81 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 69-81 2775-5215 2597-4297 10.54773/ijcnp.v5i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/94/70

oai:ojs2.journal-ijcnp.com:article/98 2022-12-02T15:55:53Z IJCNP:CR

WANITA 62 TAHUN DENGAN MALNUTRISI BERAT DAN TOXIC EPIDERMAL NECROLYSIS Arditawati, Yulin Darmono Widyastuti Malnutrition and skin problems are interrelated; therefore malnutrition will reduce the function of innate and adaptive immunity. The skin contains immune cells that is crucial for host defense. A 62-year-old female patient was diagnosed with Toxic Epidermal Necrolysis (TEN) due to an unknown drug allergy and severe malnutrition. The patient has a history of inadequate intake for 1 year ago and has worsened in the last 2 weeks due to blisters all over the skin, especially in the labium oris area after taking an unknown analgetic medication. Nutrition therapy had given with a target of 1900 kcal/day gradually increased to 2200 kcal/day through enteral and parenteral with a protein of 1.5 grams/kgIBW/day. Because of patients has history of aversion to food types such as chicken, eggs, fish, cow's milk, and dairy products, so patient had given soy-based polymeric formula and Parenteral Nutrition Supplement to achieve nutrition requirement. Supplementations administered were zinc, vitamin A, vitamin B complex, and vitamin C. At the end of the treatment period there were metabolic improvement such as wound healing without secondary skin infection and improvement of albumin serum from 2,3 g/dL to 3,3 g/ dL. Patients experienced side effects due to systemic corticosteroids in the form of moon face, severe muscle wasting, hyperglycemia, and hypertension. However, the use of systemic corticosteroids should pay attention to whether the benefits outweigh the disadvantages. Keywords: toxic epidermal necrolysis, malnutrition, corticosteroid, aversion Perhimpunan Dokter Gizi Klinik Indonesia 2022-04-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/98 10.54773/ijcnp.v5i1.98 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 47-59 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 47-59 2775-5215 2597-4297 10.54773/ijcnp.v5i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/98/68

oai:ojs2.journal-ijcnp.com:article/100 2023-06-22T00:58:35Z IJCNP:CR

TERAPI NUTRISI PADA KARSINOMA LIDAH DENGAN MALIGNANCY RESIDIF DAN SEVERE PROTEIN ENERGY MALNUTRITION Paelongan, Yosepina Suryani As’ad Asrini Safitri Marniar Abstrak Karsinoma lidah merupakan tumor ganas invasif yang berasal dari jaringan epitel yang dapat mengenai bagian oral lidah di rongga mulut atau pangkal lidah di orofaring serta  cenderung untuk bermetastasis ke bagian tubuh lainnya 1 Tujuan utama terapi nutrisi pada penderita kanker adalah untuk mempertahankan atau meningkatkan status gizi sehingga dapat memperkecil terjadinya komplikasi, meningkatkan efektivitas terapi kanker (bedah, kemoterapi, radiasi), kualitas hidup dan survival penderita. Pria, 60 tahun dikonsul dengan diagnosis Tumor Lidah Malignancy Residif dan malnutrisi berat (Subjective Global Assesment Skor C). Pasien memiliki riwayat asupan yang kurang karena gangguan menelan akibat tumor lidah sejak 2 tahun lalu, serta karena kesulitan menelan makanan karena perdarahan dari ulkus yang terdapat di bawah lidah dan tembus ke bawah dagu pasien dalam 3 hari terakhir. Terapi nutrisi  diberikan dengan target 1600 kkal secara bertahap melalui enteral dengan protein 1,2-1,4 gram/kgBB ideal/hari. Suplementasi yang diberikan adalah Zinc, Vitamin B kompleks, Vitamin C, Vitamin D, Vitamin A, Curcuma dan Kapsul ikan gabus . Pada akhir masa perawatan terdapat perbaikan metabolik seperti anemia, deplesi sistem imun, albumin dan peningkatan kapasitas fungsional. Terapi nutrisi pada kanker lidah dengan pemenuhan makronutrien dan mikronutrien yang memadai dan imunonutrisi sangat penting untuk meningkatkan status gizi dan perbaikan sistem imun. Perhimpunan Dokter Gizi Klinik Indonesia 2022-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/100 10.54773/ijcnp.v5i2.100 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 141-163 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 141-163 2775-5215 2597-4297 10.54773/ijcnp.v5i2 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/100/79 Copyright (c) 2022 Yosepina Paelongan, Suryani As’ad, Asrini Safitri, Marniar

oai:ojs2.journal-ijcnp.com:article/102 2022-12-02T15:55:54Z IJCNP:RA

PENGARUH METODE BOILING TERHADAP KADAR VITAMIN C PADA TUMBUHAN KELAKAI (STENOCHLAENA PALUSTRIS) Anisa Nabila Rahayu Ni Nyoman Sri Yuliani Dian Mutiasari Background: Kelakai (Stenochlaena palustris) is a local vegetable of the Dayak tribe that contains Vitamin C, and the majority is cooked by boiling. Research Objectives: The aim of this study was to determine the effect of the boiling method on vitamin C levels in the kelakai plant. Method: This research was an experimental study to test vitamin C on samples of fresh kelakai, boiled kelakai (3 minutes), and positive control using UV-Vis Spectrophotometry qualitatively and quantitatively. The results were then statistically tested. Results: The vitamin C content of fresh kelakai was 0.001704 mg/g, boiled kelakai for 3 minutes was 0.000846 mg/g, and the positive control was 0.006840 mg/g. The statistical Kruskal-Wallis test and post-hoc Mann-Whitney test showed that there were very significant differences in vitamin C levels in samples of fresh kelakai, boiled kelakai, and positive control (p =0,001). Conclusions: According to the results of statistical tests, there are differences in vitamin C levels in samples of fresh kelakai, boiled kelakai, and positive control. Perhimpunan Dokter Gizi Klinik Indonesia 2022-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/102 10.54773/ijcnp.v5i1.102 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 82-93 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 82-93 2775-5215 2597-4297 10.54773/ijcnp.v5i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/102/72

oai:ojs2.journal-ijcnp.com:article/106 2023-06-22T00:58:32Z IJCNP:RA

PERAN ORAL NUTRITION SUPPLEMENT (ONS) TERHADAP MALNUTRISI PADA PASIEN GANGGUAN JIWA Insani, Dina Aulia Saiful Akhyar Khairun Nida Habibah Latar Belakang: Terapi gizi berperan sebagai bagian dari terapi medis untuk membantu pengobatan dan meningkatkan kualitas hidup pasien dengan gangguan jiwa. Tujuan: untuk mengetahui peran ONS terhadap malnutrisi pada pasien gangguan jiwa. Penelitian pre-post test group design. Pasien rawat inap sejak bulan September – Februari yang dilakukan asessmen gizi. Kriteria inklusi: malnutrisi berat dan mendapat ONS. Kriteria eksklusi: pulang paksa kurang dari 3 hari, mendapat terapi nutrisi parenteral dan diagnosa penggunaan NAPZA multipel. Data dianalisis dengan paired samples t-test. Hasil: Pasien malnutrisi sebanyak 153 (27.7%). Jumlah responden 56 dengan laki-laki 30 (53.6%) dan wanita 26 (46.4%). Mayoritas menderita skizofrenia 37 (66.1%). Peningkatan berat badan rerata 1.32 kg dengan pemberian rerata ONS 500 ml/hari selama rerata 8.7 hari. Uji statistik menunjukkan hasil signifikan antara berat badan sebelum dan setelah terapi (p-value = 0.000). Kesimpulan: Didapatkan hasil signifikan antara berat badan sebelum dan setelah pemberian terapi gizi dengan ONS pada pasien malnutrisi dengan gangguan jiwa. Perhimpunan Dokter Gizi Klinik Indonesia 2022-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/106 10.54773/ijcnp.v5i2.106 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 164-168 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 164-168 2775-5215 2597-4297 10.54773/ijcnp.v5i2 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/106/78 Copyright (c) 2022 Dina Aulia Insani

oai:ojs2.journal-ijcnp.com:article/110 2022-12-02T15:55:52Z IJCNP:CR

EFFECT OF L-ARGININE SUPPLEMENTATION WITH ENDOTHELIAL FUNCTION IN DIABETES MELLITUS AND CARDIOVASCULAR DISEASE: AN EVIDENCE BASED CASE REPORT Deviana, Yusi Andayani, Diyah Eka   Abstract Background: Cardiovascular disease is the main complication that induces morbidity in diabetes mellitus patients. Endothelial function plays a role in these complications. Nitric oxide is a nitrogen-free radical produced from L-arginine, involved in several mechanisms for maintaining endothelial function to prevent cardiovascular disease and diabetes mellitus. Methods: A search for relevant literature in PubMed, Cochrane, and ProQuest was conducted. After assessing the relevancy and eligibility of the literature, two pieces of literature were selected and critically appraised. Results: There are two works of literature from systematic review and meta-analysis were found. The studies suggest pro and contra L-arginine supplementation with endothelial function in diabetes mellitus and cardiovascular disease. Conclusions: L-arginine might be the alternative supplement for cardiovascular disease and diabetes mellitus, but further analysis in improved studies is needed to confirm. Keywords: l-arginine, diabetes mellitus, cardiovascular disease, endothelial Perhimpunan Dokter Gizi Klinik Indonesia 2022-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/110 10.54773/ijcnp.v5i2.110 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 110-113 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 110-113 2775-5215 2597-4297 10.54773/ijcnp.v5i2 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/110/75 Copyright (c) 2022 Yusi Deviana, Diyah Eka Andayani

oai:ojs2.journal-ijcnp.com:article/111 2022-12-02T15:55:51Z IJCNP:CR

EFFECTIVENESS OF PREOPERATIVE CARBOHYDRATE LOADING WITH LENGTH OF HOSPITALIZATION IN NON-INVASIVE GYNECOLOGICAL SURGERY PATIENTS: AN EVIDENCE-BASED CASE REPORT Rachman, Nita Nurul Sinaga, Wina Background Carbohydrate loading is one of the steps in the preoperative procedure of Enhanced Recovery after Surgery (ERAS). The advantages of the ERAS pathway have positive effects on postoperative outcomes, including a reduction in the length of stay/LOS in hospital. Objective: This study aims to critically analyze the effectiveness of carbohydrate loading on the reduction in the length of hospital stay among patients undergoing non-invasive gynecologic surgical procedure. Methods: A search was conducted to find several literatures from PubMed, Cochrane and Scopus. This study assesses the relevance and feasibility of the literatures. The search found three selected literatures to further conduct a critical assessment. Results: A critical review was conducted towards three randomized controlled trial literatures. Two literatures showed a significant reduction in the length of stay with preoperative carbohydrate loading (p<0.001), while one literature showed an insignificant finding (p=0.684). Conclusions: Carbohydrate loading as a part of the preoperative management of ERAS could reduce the length of hospital stay among patients undergoing non-invasive gynecologic surgery procedure. Differences in the results of several studies indicate the need for further studies using the similar intervention method. Keywords: enhanced recovery after surgery, gynecologic surgery, carbohydrate loading, length of stay. Perhimpunan Dokter Gizi Klinik Indonesia 2022-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/111 10.54773/ijcnp.v5i2.111 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 102-109 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 102-109 2775-5215 2597-4297 10.54773/ijcnp.v5i2 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/111/74 Copyright (c) 2022 Nita Nurul Rachman, Wina Sinaga

oai:ojs2.journal-ijcnp.com:article/112 2023-06-22T00:58:29Z IJCNP:CR

EFEKTIVITAS SUPLEMENTASI VITAMIN K TERHADAP KONTROL GLIKEMIK PADA PASIEN DIABETES MELITUS TIPE 2: EVIDENCE BASED CASE REPORT Hanifa, Rizka Nurul Ratna Mutu Manikam Latar belakang: Terdapat beberapa bukti penelitian prospektif observasional dan uji klinis yang menunjukkan penurunan risiko diabetes melitus (DM) dengan suplementasi vitamin K melalui perannya terhadap respon insulin, efek insulinotropik, dan modulasi vitamin K-dependent protein. Tujuan penelitian: Studi ini bertujuan untuk menelaah secara kritis mengenai efek suplementasi vitamin K terhadap kontrol glikemik pada pasien DM tipe 2. Metode: Pencarian literatur dilakukan pada 3 database yaitu PubMed, Cochrane dan Scopus. Literatur yang sesuai dengan PICO kemudian diseleksi berdasarkan kriteria eligibilitas dan dilakukan telaah kritis. Hasil: Terpilih 2 artikel dengan studi randomized controlled trial (RCT). Kedua artikel tersebut menunjukkan pengaruh yang signifikan setelah pemberian suplemen vitamin K terhadap status glikemik pada pasien DM tipe 2. Artikel pertama menunjukkan dengan pemberian kapsul MK-7 sebesar 200 μg/hari selama 12 minggu, nilai glukosa darah puasa (GDP) (MD=24,37; 95% IK: 3,37-45,37; p: 0,02) dan HbA1c (MD=1,23; 95% IK: 0,21-2,26; p: 0,01) secara signifikan lebih rendah pada kelompok MK-7 dibandingkan plasebo. Artikel kedua juga menunjukkan dengan memberikan MK-7 180 μg dua kali sehari selama 12 minggu, kadar GDP (effect size (ES)=−0,68; p-adjusted=0,031) dan HbA1c (ES=−0,36; p-adjusted=0,004) pada kelompok Mk-7 secara signifikan lebih rendah dibandingkan dengan plasebo. Kesimpulan: Kedua artikel menunjukkan hasil yang konsisten dalam menurunkan kadar GDP dan HbA1c. Studi dengan ruang lingkup terapi yang membahas topik ini masih terbatas, sehingga diperlukan studi selanjutnya untuk mengonfirmasi temuan ini dan untuk mendukung rekomendasi suplementasi vitamin K dalam regimen terapi pasien DM tipe 2. Kata kunci: vitamin K, diabetes, kontrol glikemik, glukosa darah puasa, HbA1c Perhimpunan Dokter Gizi Klinik Indonesia 2022-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/112 10.54773/ijcnp.v5i2.112 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 125-140 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 125-140 2775-5215 2597-4297 10.54773/ijcnp.v5i2 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/112/77 Copyright (c) 2022 Rizka Hanifa

oai:ojs2.journal-ijcnp.com:article/113 2023-06-22T00:58:26Z IJCNP:RA

AN EFFECTIVENESS OF OMEGA 3 SUPPLEMENTATION ON CLINICAL SYMPTOMS IMPROVEMENT AND CLINICAL PARAMETERS OF COVID-19 Yanti, Novi Lily Indriani Octovia Abstract Background Coronavirus disease 2019 (COVID-19) infection is a disease with high morbidity and mortality rates worldwide. This viral infection can cause metabolic and clinical changes that affect the patient's condition. Omega 3 polyunsaturated fatty acids (ω3-PUFAs) are important mediators of anti-inflammatory and immune response. Thus, it can reduce clinical symptoms of COVID-19 patients. Objective: To know the effect of omega 3 supplementation in improving clinical symptoms and clinical parameters of COVID 19. Methods: Article searches were conducted using advanced searching by combining MesH Terms and abstracts/titles in the Pubmed, Cochrane Library, and Scopus databases. The search found two selected literatures to further conduct a critical assessment. Results:Two articles were selected based on the eligibility criteria and conformity with the Problem Intervention Comparison Outcome (PICO). Study conducted by Sedighiyan et al.,1 showed that there were significant changes in clinical symptoms of COVID-19 patients such as pain, fatigue (p< 0.001), increased appetite (p=0.003), decreased Erythrocyte Sedimentation Rate (ESR) values (p < 0.002), and decreased C-reactive protein (CRP) values ​​(p<0.001). Study conducted by Doaei et al.,2 showed that there was significant decrease in pH (p=0.001), HCO3 (p = 0.001), Be (p = 0.001), and creatinine (p = 0.002), thereby improving clinical symptoms of COVID-19 patients. Conclusion: Omega 3 supplementation can improve clinical symptoms and clinical parameters of COVID 19. However, further research is needed with a larger sample, a longer duration, and with dose adjustment of omega 3 supplementation. Keywords:COVID-19, omega 3 fatty acids, clinical symptoms and clinical parameters improvement Perhimpunan Dokter Gizi Klinik Indonesia 2022-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/113 10.54773/ijcnp.v5i2.113 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 166-174 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 166-174 2775-5215 2597-4297 10.54773/ijcnp.v5i2 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/113/81 Copyright (c) 2022 Novi Yanti

oai:ojs2.journal-ijcnp.com:article/114 2023-11-08T03:11:44Z IJCNP:CR

EFFECTIVENESS OF PROBIOTIC SUPPLEMENT ON HELICOBACTER PYLORI INFECTION ERADICATION IN GASTRIC ULCERS Sulistyanti Dian Rachmawati Lestari, Wiji Background: Helicobacter pylori colonizes the gastric mucosa in 50% of the human population. H. pylori infection causes several upper gastrointestinal tract diseases such as chronic gastritis, peptic ulcer, duodenal ulcer, and gastric cancer. H. pylori is also associated with a high risk of developing gastric adenocarcinoma. The World Health Organization classifies H. pylori infection as a class 1 carcinogen. Giving probiotics may improve the immune system and suppress the effects of pathogens. However, mixed results were obtained from the use of various kinds of bacteria and fungi as probiotics. Objective: To determine the effectiveness of probiotic supplementation against the eradication of Helicobacter pylori infection in gastric ulcers. Conclusion: The effectiveness uses of probiotics to eradicate H. pylori has not been proven. It will take clinical trials with a sufficient number of subjects and certain probiotic strains to be able to determine the type of strain, dosage, duration of use, and side effects that can be caused. Perhimpunan Dokter Gizi Klinik Indonesia 2023-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/114 10.54773/ijcnp.v6i1.114 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 6 No. 1 (2023): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 22-29 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 6 No 1 (2023): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 22-29 2775-5215 2597-4297 10.54773/ijcnp.v6i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/114/89 Copyright (c) 2023 Sulistyanti Dian Rachmawati, Wiji Lestari

oai:ojs2.journal-ijcnp.com:article/117 2023-11-06T03:10:27Z IJCNP:CR

SUPLEMENTASI ASAM FOLAT PRAKONSEPSI DALAM PENCEGAHAN BIBIR SUMBING : EVIDENCE - BASED CASE REPORT Jessica, Amelia Nurul Ratna Mutu Manikam Bibir sumbing merupakan kelainan bawaan yang sering dijumpai pada bayi baru lahir, terutama di negara berkembang. Faktor risikonya antara lain paparan terhadap rokok dan bahan kimia, konsumsi alkohol, serta asupan mikronutrien yang tidak memadai selama kehamilan. Dosis suplementasi asam folat yang lebih tinggi pada masa prakonsepsi berhubungan dengan penurunan risiko bibir sumbing. Tujuan: Mengetahui hubungan antara suplementasi asam folat prakonsepsi dengan risiko terjadinya bibir sumbing. Metode: Pencarian literatur dilakukan dengan advanced searching pada Pubmed, Cochrane Library, Scopus, dan ProQuest dengan kriteria eligibilitas yang ditentukan oleh penulis. Hasil: Studi systematic review-meta analisis oleh Jayarajan, et al. (2019) menjelaskan bahwa terdapat hubungan kuat antara suplementasi asam folat dosis tinggi dengan bibir sumbing. Studi kasus-kontrol yang menilai hubungan suplementasi asam folat prakonsepsi dengan penurunan risiko bibir sumbing dilakukan oleh 2 peneliti. Penelitian Xu W, et al. (2021) menjelaskan bahwa suplementasi asam folat prakonsepsi menurunkan risiko bibir sumbing (aOR = 0,52, 95% CI 0,30-0,90), sedangkan penelitian Mendonca VJ, et al. (2019) menjelaskan bahwa untuk mendapatkan efek samping pada 1 pasien diperlukan 71 pasien dengan suplementasi asam folat selama 1 tahun. Kesimpulan: Berdasarkan dua penelitian didapatkan hasil bahwa suplementasi asam folat prakonsepsi dapat menurunkan risiko bibir sumbing, namun diperlukan penelitian lebih lanjut. Perhimpunan Dokter Gizi Klinik Indonesia 2023-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/117 10.54773/ijcnp.v6i1.117 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 6 No. 1 (2023): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 13-21 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 6 No 1 (2023): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 13-21 2775-5215 2597-4297 10.54773/ijcnp.v6i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/117/88 Copyright (c) 2023 Amelia Jessica, Nurul Ratna Mutu Manikam

oai:ojs2.journal-ijcnp.com:article/130 2023-06-22T00:58:23Z IJCNP:RA

ASSOCIATION BETWEEN ENTERAL NUTRITION AVAILABILITY WITH NUTRITIONAL FULFILLMENT AND NUTRITIONAL STATUS IN HEAD AND NECK CANCER PATIENTS Marino, Marvin Eka Andayani, Diyah Giselvania, Angela Background: The availability of enteral nutrition is one of nutritional intervention that can be given to prevent a decrease in nutritional intake and nutritional status in HNC patient. Research objective: This study aims to see the correlation between the availability of enteral nutrition with nutritional fulfillment and nutritional status. Methodology: A cross sectional study was conducted on adult subjects with HNC after radiation therapy at the RSCM radiotherapy outpatient clinic. Nutritional fulfillment was assessed by semi-quantitative FFQ while nutritional status was measured by calculating body mass index (BMI). Research results: Forty-one subjects mean age of 51 years participated in the study. The mean BMI of subjects with enteral nutrition was lower than those on oral nutrition, 18,2±2,6 kg/m2 compared to 21,2±3,5 kg/m2 respectively. The mean total energy intake of subjects with enteral nutrition route was higher, which was 1498,1±430,6 Kcal/day compared to 1291,4±393,3 Kcal/day. There was a moderate negative correlation between the availability of enteral nutrition and nutritional status (r=-0,346, p=0,027), meanwhile there was a weak positive correlation with nutritional fulfillment (r=0,216, p=0,174). However, in this study we found that the proportion of subjects with enteral nutrition who experienced a decrease in BMI was less than the proportion of subjects on the oral route, which was 22,2% compared to 43,8% respectively. Conclusion: There is a moderate negative correlation between the availability of enteral nutrition with nutritional status and a weak positive correlation with nutritional fulfillment which is still influenced by confounding factors. Perhimpunan Dokter Gizi Klinik Indonesia 2022-08-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/130 10.54773/ijcnp.v5i2.130 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 5 No. 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 185-196 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 5 No 2 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 185-196 2775-5215 2597-4297 10.54773/ijcnp.v5i2 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/130/82 Copyright (c) 2022 Marvin Marino, Diyah Eka Andayani, Angela Giselvania

oai:ojs2.journal-ijcnp.com:article/133 2023-09-10T11:44:43Z IJCNP:CR

THE EFFECTS OF CURCUMIN SUPPLEMENTATION ON GLYCAEMIC INDEX IN WOMEN WITH POLYCYSTIC OVARIAN SYNDROME: AN EVIDENCE BASED CASE REPORT Kumala, Marcia Mutu Manikam, Nurul Ratna Background: PCOS is the most common cause of infertility around the world. PCOS is associated with impaired glucose tolerance and higher tendency to develop type 2 diabetes. Curcumin, which is known for its anti-inflammatory, antioxidant, and antidiabetic properties, may show promising effect in regulating blood glucose. Objective: This study aims to evaluate the effect of curcumin supplementation on improving glycaemic profile in women with PCOS. Methods: Literature searching was conducted by advanced searching in Pubmed, Cochrane Library, Scopus, and ProQuest database using MeSH Terms combined with Title/Abstract. After removing duplicates, the literatures were screened based on the eligibility criteria. Critical appraisal and level of evidence of the selected literatures were determined based on Oxford Centre for Evidence-Based Medicine. Results: Two selected literatures were relevant to answer our clinical question. The first literature is a systematic review/meta-analysis study by Chien et al (2021) and the latter is a randomized controlled trial by Asan et al (2020). Both literatures show that curcumin supplementation is beneficial in improving glycaemic profile in PCOS patients. These effects were marked by lower fasting blood glucose, insulin level, and HOMA-IR in curcumin group compared to the control group. Conclusion: Curcumin supplementation for at least 6 weeks significantly improve glycaemic profile in women with PCOS. Curcumin supplementation is also considered safe and well tolerable. However, more studies are needed to investigate further regarding the long-term effects of curcumin supplementation. Keywords: curcumin, turmeric, polycystic ovarian syndrome, glycaemic profile Perhimpunan Dokter Gizi Klinik Indonesia 2023-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/133 10.54773/ijcnp.v6i1.133 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 6 No. 1 (2023): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 1-12 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 6 No 1 (2023): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 1-12 2775-5215 2597-4297 10.54773/ijcnp.v6i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/133/83 Copyright (c) 2023 Marcia Kumala, Nurul Ratna Mutu Manikam

oai:ojs2.journal-ijcnp.com:article/156 2023-11-04T13:31:48Z IJCNP:RA

HUBUNGAN PHASE ANGLE DENGAN TINGKAT KEPARAHAN INFARK MIOKARD Kristiansen, Rosa Niken Puruhita Febe Christianto Hertanto Wahyu Subagio Enny Probosari Latar belakang : Phase angle (PhA) yang merupakan indikator integritas seluler mungkin berhubungan dengan tingkat keparahan IM yang tercermin dari penanda cedera miosit yaitu kadar troponin. Tujuan : Menganalisis hubungan PhA dengan tingkat keparahan IM. Metode : Penelitian observasional, melibatkan 40 subjek dengan IM yang memenuhi kriteria inklusi dan eksklusi. Tingkat keparahan IM diukur dari kadar troponin I, PhA didapatkan dari bioelectrical impedance analysis, dan data komorbid diambil dari rekam medis pasien. Uji hipotesis menggunakan analisis bivariat untuk melihat hubungan phase angle dan beberapa komorbid dengan tingkat keparahan IM. Hasil :  Mayoritas subyek penelitian berjenis kelamin laki-laki (82,5%), rerata usia 56,1 tahun, dan rerata IMT 25,56 kg/m2. Dislipidemia merupakan jenis komorbid yang paling banyak diderita (92,5%) dan 62,5% subyek penelitian memiliki 2 atau lebih komorbid. Hasil analisis bivariat PhA, jenis komorbid, jumlah komorbid, usia, IMT, dan jenis kelamin terhadap kadar troponin I adalah tidak signifikan (p>0,05). Kesimpulan : PhA, diabetes, hipertensi, dislipidemia, jumlah komorbid, usia, IMT, dan jenis kelamin tidak berhubungan dengan tingkat keparahan IM. Kata kunci : BIA, komorbid kardiovaskular, phase angle, tingkat keparahan infark miokard Perhimpunan Dokter Gizi Klinik Indonesia 2023-09-21 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/156 10.54773/ijcnp.v6i1.156 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 6 No. 1 (2023): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 42-49 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 6 No 1 (2023): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 42-49 2775-5215 2597-4297 10.54773/ijcnp.v6i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/156/86 Copyright (c) 2023 Rosa Kristiansen, Niken Puruhita, Febe Christianto, Hertanto Wahyu Subagio, Enny Probosari

oai:ojs2.journal-ijcnp.com:article/174 2023-11-04T13:37:40Z IJCNP:RA

REDUCED BODY MASS INDEX BUT NOT FAT MASS IN ANTHRACYCLINE-BASED CHEMOTHERAPY OF LOCALLY ADVANCED BREAST CANCER PATIENTS Rachmawati, Isma Yohana, Raden Amam, Bambang Zuhairini, Yenni Background: Breast cancer is a cancer disease with the highest proportion of new cases and the proportion of deaths it causes is quite high at 6.9%. Cancer patients who use anthracycline-based chemotherapy experience loss of body weight, muscle, body cell mass, distribution of extracellular fluid expansion and reduced intracellular air. This study was to determine the change of the Body Mass index (BMI) and body composition of patients with locally advanced breast cancer (stage IIIA, IIIB and IIIC) who had undergone anthracycline-based chemotherapy.Methods: This anthracycline-based observational analytical study of pre and post chemotherapy was conducted with a cross-sectional approach. Subjects were measured height by microtoise; weight, body composition, daily calorie intake (DCI) and basal metabolic rate (BMR) as measured by Bioelectrical Impendance Analysis (BIA).Results: 47 locally advanced breast cancer patients underwent anthracycline-based chemotherapy. Based on the Wilcoxon statistical test, 6 variables with a 95% confidence level (p<0.05) showed a decrease in the value 5 variables, namely BMI, total body water (TBW), visceral fat, skeletal muscle mass and skeletal bone mass. Meanwhile, body fat showed a p value=0.224. The changes of variable confounding, DCI decrease (p=0.004), but BMR increase not significantly (p=0.795).Conclusion: There is an effect of chemotherapy on nutritional status of BMI, TBW, visceral fat, skeletal muscle mass and bone mass in patients with locally advanced breast cancer who underwent anthracycline-based chemotherapy, which may the result of the calorie intake decreased, but not on body fat Perhimpunan Dokter Gizi Klinik Indonesia 2023-09-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/174 10.54773/ijcnp.v6i1.174 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 6 No. 1 (2023): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 50-58 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 6 No 1 (2023): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 50-58 2775-5215 2597-4297 10.54773/ijcnp.v6i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/174/87 Copyright (c) 2023 Isma Rachmawati, Raden Yohana, Bambang Amam, Yenni Zuhairini

oai:ojs2.journal-ijcnp.com:article/183 2023-11-04T13:25:39Z IJCNP:RA

PROFIL ANTROPOMETRIK, VITAMIN D, B12, FOLAT, DAN FERITIN PASIEN OBES PRABEDAH BARIATRIK DI POLIKLINIK GIZI RUMAH SAKIT SUMBER WARAS Hayuningtyas, Anastasia Lady Dhita Alfara Tjandraningrum Tambunan, Victor Halim, Lukman Kumala, Meilani Titus, Johana Obese patients, especially patients with severe obesity and requiring bariatric surgery, have a high prevalence of nutrient deficiencies. This study aims to determine some of the basic characteristics of patients undergoing bariatric surgery so that they can be used as supporting data for post-bariatric surgery nutrition medical therapy, particularly in the provision of food sources and micronutrient supplementation which can be deficient due to anatomic and physiological alterations after the surgery. The study was conducted on 55 preoperative bariatric patients by assessing age, gender, and degree of obesity based on body mass index (BMI), serum vitamin D and B12 levels, erythrocyte folic acid, and serum ferritin of subjects. The study is descriptive with a cross-sectional design. Subjects were taken by consecutive sampling. The results showed that the mean age of preoperative bariatric patients was 36 ± 7.1 years; most (85.5%) were women. Most subjects (34.5%) had BMI of 35­–39.9 kg/m2. Vitamin D deficiency was present in most (75.6%) of the study subjects, but most had serum vitamin B12 levels, erythrocyte folic acid levels, and serum ferritin levels within normal limits. This study shows that the basic profile of patients undergoing bariatric surgery is primarily late adults, classified as severe obese and having vitamin D deficiency. Keywords: Obesity, Prebariatric, Serum Vitamin D, Serum Vitamin B12, Erythrocyte Folic Acid, and Serum Ferritin. Perhimpunan Dokter Gizi Klinik Indonesia 2023-02-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/183 10.54773/ijcnp.v6i1.183 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 6 No. 1 (2023): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 30-41 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 6 No 1 (2023): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 30-41 2775-5215 2597-4297 10.54773/ijcnp.v6i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/183/85 Copyright (c) 2023 Anastasia Hayuningtyas, Lady Dhita Alfara, Tjandraningrum, Victor Tambunan, Lukman Halim, Meilani Kumala, Johana Titus

oai:ojs2.journal-ijcnp.com:article/191 2024-07-05T23:13:24Z IJCNP:CR

EFFECTS OF VITAMIN D ADMINISTRATION FOR WOUND HEALING IN PATIENTS WITH DIABETIC FOOT ULCERS: EVIDENCE BASED CASE REPORT Badralany, Felianty Nurul Ratna Mutu Manikam Diabetes mellitus can cause microvascular and macrovascular complications.  Diabetic foot ulcer is the complications that often occur in DM patients, which is as much as 10%-25%. In Indonesia, the incidence of diabetic foot ulcers is 12% and DM patients can be at risk of diabetic foot ulcers as much as 55.4%. The mortality rate that occurs as a result of diabetic foot ulcers can reach around 15-30%. Patients who have diabetic foot ulcers significantly decreased vitamin D levels.  This study aims to determine the effectiveness of vitamin D supplementation for wound healing in diabetic foot ulcers. Perhimpunan Dokter Gizi Klinik Indonesia 2024-07-04 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/191 10.54773/ijcnp.v6i1.191 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 6 No. 1 (2023): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 1-11 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 6 No 1 (2023): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); 1-11 2775-5215 2597-4297 10.54773/ijcnp.v6i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/191/91 Copyright (c) 2024 Felianty Badralany, Nurul Ratna Mutu Manikam

oai:ojs2.journal-ijcnp.com:article/243 2025-12-31T08:57:06Z IJCNP:CR

PERIOPERATIVE MEDICAL NUTRITIONAL THERAPY IN A SEVERELY MALNOURISHED PATIENT WITH AMPULLA OF VATER CARCINOMA POST WHIPPLE PROCEDURE: A CASE REPORT Ratha, I Putu Prayoga Abstract Background : The ampulla of Vater carcinoma is a rare gastrointestinal malignancy but has a better prognosis than pancreatic cancer. Severe malnutrition is common in patients with gastrointestinal cancer and worsens clinical outcomes. Objective: To report the implementation of structured perioperative nutrition therapy in a severely malnourished patient with carcinoma of the ampulla of Vater. Methods: Case report of a 51-year-old woman with severe malnutrition and obstructive jaundice, who underwent a Whipple procedure . Nutritional status assessment was performed using Subjective Global Assessment (SGA), anthropometry, and hand grip strength (HGS). Perioperative nutritional therapy was carried out in stages, with clinical and laboratory monitoring. Results: Nutrition therapy was started preoperatively with the ERAS method and continued gradually postoperatively through enteral and parenteral routes, until the patient was able to accept a full oral diet and vitamin supplementation. The target energy of 1840 kcal and protein 78 g/day was achieved within 7 days. Clinical status and physical function improved during treatment. Conclusion: Appropriate perioperative nutritional therapy supports metabolic recovery, improves nutritional status, and enhances clinical outcomes in patients with advanced gastrointestinal cancer undergoing major surgery. Keywords : severe malnutrition, ampullary carcinoma , perioperative nutritional medical therapy, Whipple procedure Perhimpunan Dokter Gizi Klinik Indonesia 2025-12-24 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/243 10.54773/ijcnp.v7i1.243 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 7 No. 1 (2026): IJCNP IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 7 No 1 (2026): IJCNP 2775-5215 2597-4297 10.54773/ijcnp.v7i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/243/95 Copyright (c) 2025 I Putu Prayoga Ratha

oai:ojs2.journal-ijcnp.com:article/244 2025-12-20T08:39:24Z IJCNP:CR

THE EFFECTS OF VITAMIN D SUPPLEMENTATION ON DISEASE ACTIVITY IN SYSTEMIC LUPUS ERYTHEMATHOSUS PATIENTS: AN EVIDENCE-BASED CASE REPORT Faridahanum, Santri Dwizamzami Steffi Sonia Background: Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease characterized by the production of autoantibodies and multisystem involvement, predominantly affecting women of reproductive age. Vitamin D is known to have immunomodulatory effects, including inhibition of T and B cell activation and suppression of pro-inflammatory cytokine production. Objectives: This evidence-based case report aims to evaluate the effect of vitamin D supplementation on disease activity in SLE. Methods: A literature search was conducted using PubMed, Scopus, and Cochrane. Medical Subject Headings (MeSH) terms and relevant keywords based on the clinical question components were applied. All retrieved literature was screened using predefined eligibility criteria, followed by a critical appraisal of eligible studies. Results: One meta-analysis of randomized controlled trials (RCTs) and two RCTs met the eligibility criteria. Almost all of the included studies recruited patients with SLE who had vitamin D deficiency/insuficiency. The methodological validity of all three studies was considered acceptable. The studies demonstrated heterogeneity in terms of baseline disease activity levels among their study populations. The meta-analysis and one of the RCTs reported non-significant results, while the other RCT showed a significant improvement in disease activity following vitamin D supplementation. Conclusion: Current evidence is insufficient to recommend vitamin D supplementation as an adjuvant therapy for improving disease activity in patients with SLE and further research is needed. Perhimpunan Dokter Gizi Klinik Indonesia 2025-09-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/244 10.54773/ijcnp.v7i1.244 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 7 No. 1 (2026): IJCNP; 12-24 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 7 No 1 (2026): IJCNP; 12-24 2775-5215 2597-4297 10.54773/ijcnp.v7i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/244/93 Copyright (c) 2026 Santri Dwizamzami Faridahanum, Steffi Sonia

oai:ojs2.journal-ijcnp.com:article/250 2026-04-09T02:37:40Z IJCNP:RA

The PHASE ANGLE AND ITS CLINICAL RELEVANCE TO MALNUTRITION AND LOW-GRADE INFLAMMATION AMONG HEMODIALYSIS PATIENTS: A CROSS-SECTIONAL PERSPECTIVE WIDIASIH, ESTI Background: Patients with chronic kidney disease (CKD) undergoing routine hemodialysis are prone to chronic inflammation and malnutrition, two interrelated conditions that worsen clinical outcomes. The phase angle obtained from bioelectrical impedance analysis (BIA) reflects cell membrane integrity and nutritional status and is suspected to correlate with inflammatory biomarkers such as TNF-α. Objective: To analyze the relationship between phase angle and Dialysis Malnutrition Score (DMS) on TNF-α levels in routine hemodialysis patients. Methods: A cross-sectional analytical study was conducted on 50 routine hemodialysis patients in a clinic in Semarang. Data collected included age, sex, duration of hemodialysis, BMI, skeletal muscle mass (SMM), DMS, phase angle, and TNF-α levels. Data were analyzed using Pearson correlation and multiple linear regression. Results: The average age of participants was 52.38 years, and the average phase angle was 5.05. Pearson correlation showed a significant negative correlation between phase angle and TNF-α levels (r = -0.587; p = 0.000), while DMS showed a positive correlation (r = 0.368; p = 0.009). In the regression model, only phase angle was a significant predictor of TNF-α (β = -0.471; p < 0.001). Conclusion: Phase angle has a significant negative correlation with TNF-α levels, suggesting its potential as a non-invasive marker for inflammation monitoring in hemodialysis patients. DMS was not significant in the multivariate model. Further studies are recommended to explore causal relationships and longitudinal assessments. Keyword : Hemodialysis, Phase Angle, TNF-α, Malnutrition, DMS, Chronic Inflammation Perhimpunan Dokter Gizi Klinik Indonesia 2025-08-02 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/250 10.54773/ijcnp.v7i1.250 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 7 No. 1 (2026): IJCNP; 1-11 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 7 No 1 (2026): IJCNP; 1-11 2775-5215 2597-4297 10.54773/ijcnp.v7i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/250/92 Copyright (c) 2026 ESTI WIDIASIH https://creativecommons.org/licenses/by-sa/4.0

oai:ojs2.journal-ijcnp.com:article/252 2026-01-29T09:59:08Z IJCNP:RA

THE EFFECT OF VITAMIN C INTAKE ON SKIN MOISTURE IN YOUNG ADULTS Stefani, Shiela Background: Dry skin affects 50%–80% of Indonesia. Data from the Geriatric Department of the Dermatology and Venereology Clinic at Dr. Cipto Mangunkusumo Hospital (RSCM) in Jakarta between 2008 and 2013 indicate that dry skin is one of the ten most prevalent illnesses. Objective: Regarding skin moisture, this study tries to determine the impact of vitamin C on young adult participants. Methods: This is an observational analytical study with a quasi-experimental design carried out at Maranatha Christian University in Bandung. Medical students between 19 and 29 years old at Maranatha Christian University's Faculty of Medicine served as the study participants. Based on gender, sixty participants were split into two groups. TEWL levels were measured using the Skin Moisture Analyzer FCM-1. Vitamin C intake was obtained from a food frequency questionnaire containing food sources of vitamin C, which was then analyzed using the Nutrisurvey-2007 program, as well as vitamin C from supplementation. Results: Employing paired t-tests, the p-value for both male and female groups was <0.001, suggesting a substantial change in skin moisture levels before and after vitamin C intake. Conclusion: Young adults' skin moisture levels are affected by vitamin C intake. Perhimpunan Dokter Gizi Klinik Indonesia 2026-01-26 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/252 10.54773/ijcnp.v7i1.252 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 7 No. 1 (2026): IJCNP; 1-16 IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 7 No 1 (2026): IJCNP; 1-16 2775-5215 2597-4297 10.54773/ijcnp.v7i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/252/97 Copyright (c) 2026 Shiela Stefani

oai:ojs2.journal-ijcnp.com:article/260 2025-12-30T08:52:24Z IJCNP:CR

The Role Of Synbiotic Supplementation In Improving Bowel Movement Frequency In A Burn Patient With 32% Total Body Surface Area And Constipation: A Case Report Cindy Herno Chrysela Wina Sinaga Aditya Wardhana Diyah Eka Andayani Background: Severe burns cause microbiota dysbiosis, impaired intestinal motility, and constipation, worsening patient conditions and prolonging hospitalization. Research Objective: To evaluate the effectiveness of synbiotic supplementation in improving bowel movement frequency in burn patients. Case Illustration: A study conducted in the Burn High Care Unit at RSUPN Cipto Mangunkusumo involved a 42-year-old male patient with 32% TBSA burns and a history of kidney transplantation. Treatments included debridement, skin grafts, electrolyte correction, and synbiotic supplementation starting on day 6. During 29 days, energy intake, fiber intake, bowel movement frequency, and clinical status were monitored, showing significant improvements until discharge. Discussion: The 42-year-old male patient with 32% TBSA burns experienced impaired intestinal motility and constipation consistent with microbiota dysbiosis and decreased SCFA due to severe burns. The patient received enteral nutrition and Rillus® synbiotic supplementation from day 6, theoretically enhancing beneficial bacterial colonization and intestinal motility. Bowel movement frequency improved from day 7, indicating synbiotic-related benefits. Micronutrient supplementation according to ESPEN supported wound healing and immunity. Clinical condition and nutritional status improved with significant wound healing until discharge on day 30. Conclusion: Synbiotic supplementation effectively increased bowel movement frequency and improved intestinal function in severe burn patients with constipation.   Keywords: Severe burn, microbiota dysbiosis, synbiotic, constipation, intestinal motility, bowel movement frequency. Perhimpunan Dokter Gizi Klinik Indonesia 2025-12-24 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/260 10.54773/ijcnp.v7i1.260 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 7 No. 1 (2026): IJCNP IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 7 No 1 (2026): IJCNP 2775-5215 2597-4297 10.54773/ijcnp.v7i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/260/96 Copyright (c) 2025 Cindy Herno Chrysela, Wina Sinaga, Aditya Wardhana, Diyah Eka Andayani

oai:ojs2.journal-ijcnp.com:article/263 2026-01-01T08:57:48Z IJCNP:SR

THE EFFECT OF PROBIOTIC ADMINISTRATION ON THE GUT–LUNG AXIS IN REDUCING THE INCIDENCE OF PNEUMONIA: A SYSTEMATIC REVIEW fiohana, puput Introduction: Pneumonia is a major cause of illness and death, especially in critically ill patients. Probiotics have been proposed as a supportive intervention to enhance immune function, maintain gut microbial balance, and strengthen the intestinal barrier against inflammation. Research objectives: The aim of this review is to systematically identify relevant evidence regarding the relationship between probiotics and pneumonia. Methodology: The article employs a systematic review as its methodology. A comprehensive literature search was conducted across PubMed, Google Scholar, and Scopus. The selection of articles for the review was based on established inclusion and exclusion criteria, adhering to the guidelines set forth by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Result: Based on 50 articles, 10 articles were filtered that met the inclusion criteria. The reviewed studies indicated that probiotic supplementation may reduce the severity of pneumonia, particularly ventilator-associated pneumonia (VAP), and improve immune response in critically ill patients. Other research supports that probiotic administration can reduce ICU stays and improve overall good immunity. However, other studies have shown that probiotic administration does not affect the length of stay or therapy in the ICU for pneumonia patients. Conclusion: The administration of probiotics in pneumonia patients provides multiple benefits, particularly by enhancing immunity through the modulation of macrophages within the gut–lung axis. Key words: immune system, pneumonia, probiotik, systematic review Perhimpunan Dokter Gizi Klinik Indonesia 2025-12-22 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://journal-ijcnp.com/index.php/IJCNP/article/view/263 10.54773/ijcnp.v7i1.263 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 7 No. 1 (2026): IJCNP IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 7 No 1 (2026): IJCNP 2775-5215 2597-4297 10.54773/ijcnp.v7i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/263/94 Copyright (c) 2025 puput fiohana

oai:ojs2.journal-ijcnp.com:article/270 2026-02-04T05:54:39Z IJCNP:CR

Nutritional management of high output enterocutaneous fistula: Case report. Sari, Eka Maya Enterocutaneous fistula is a common post-operative gastrointestinal surgery complication with high morbidity and mortality rate. High morbidity and mortality rate in enterocutaneous fistula is due to malnutrition, dehydration and electrolyte disturbances. Comprehensive management needed to support optimal therapy of enterocutaneous fistula including nutritional therapy. We present of a case of an enterocutaneous fistula after gastrointestinal surgery which cause malnutrition. This case demonstrates that adequate nutritional management of enterocutaneous fistula plays important role in healing process.   Perhimpunan Dokter Gizi Klinik Indonesia 2026-02-04 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/vnd.openxmlformats-officedocument.wordprocessingml.document https://journal-ijcnp.com/index.php/IJCNP/article/view/270 IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN); Vol. 7 No. 1 (2026): IJCNP IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN; Vol 7 No 1 (2026): IJCNP 2775-5215 2597-4297 10.54773/ijcnp.v7i1 eng https://journal-ijcnp.com/index.php/IJCNP/article/view/270/98 Copyright (c) 2025 Eka Maya Sari https://creativecommons.org/licenses/by-sa/4.0