AN EFFECTIVENESS OF OMEGA 3 SUPPLEMENTATION ON CLINICAL SYMPTOMS IMPROVEMENT AND CLINICAL PARAMETERS OF COVID-19
Main Article Content
Abstract
Abstract
Background
Coronavirus disease 2019 (COVID-19) infection is a disease with high morbidity and mortality rates worldwide. This viral infection can cause metabolic and clinical changes that affect the patient's condition. Omega 3 polyunsaturated fatty acids (ω3-PUFAs) are important mediators of anti-inflammatory and immune response. Thus, it can reduce clinical symptoms of COVID-19 patients.
Objective: To know the effect of omega 3 supplementation in improving clinical symptoms and clinical parameters of COVID 19.
Methods: Article searches were conducted using advanced searching by combining MesH Terms and abstracts/titles in the Pubmed, Cochrane Library, and Scopus databases. The search found two selected literatures to further conduct a critical assessment.
Results:Two articles were selected based on the eligibility criteria and conformity with the Problem Intervention Comparison Outcome (PICO). Study conducted by Sedighiyan et al.,1 showed that there were significant changes in clinical symptoms of COVID-19 patients such as pain, fatigue (p< 0.001), increased appetite (p=0.003), decreased Erythrocyte Sedimentation Rate (ESR) values (p < 0.002), and decreased C-reactive protein (CRP) values (p<0.001). Study conducted by Doaei et al.,2 showed that there was significant decrease in pH (p=0.001), HCO3 (p = 0.001), Be (p = 0.001), and creatinine (p = 0.002), thereby improving clinical symptoms of COVID-19 patients.
Conclusion:
Omega 3 supplementation can improve clinical symptoms and clinical parameters of COVID 19. However, further research is needed with a larger sample, a longer duration, and with dose adjustment of omega 3 supplementation.
Keywords:COVID-19, omega 3 fatty acids, clinical symptoms and clinical parameters improvement
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
This journal provides direct open access to its content on the principle that making research freely available to the public supports greater global knowledge exchange. IJCNP Journal offers all journal article writers to have their research openly available, free access and time-limited.
All articles published in Open Access will be immediately and permanently free for everyone, where the articles can be read and downloaded. With alicense CC BY-SA,
Authors retain copyright to their articles, but authors allow others to use the published content in whole or in part as long as the original work is cited properly. Users (redistributors) of IJCNP are asked to cite the original source, including the name of the author, IJCNP as the source of initial publication, year of publication, number and volume.
Copyright includes the exclusive right to reproduce and transmit this article in all forms and media, including reprints, photographs, microfilm and other similar reproductions, and translations thereof. Reproduction of any part of this journal, its database storage and transmission in any form or medium, such as electronic, electrostatic and mechanical copies, photocopying, recording, magnetic media.
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.