REDUCED BODY MASS INDEX BUT NOT FAT MASS IN ANTHRACYCLINE-BASED CHEMOTHERAPY OF LOCALLY ADVANCED BREAST CANCER PATIENTS
Main Article Content
Abstract
Background: Breast cancer is a cancer disease with the highest proportion of new cases and the proportion of deaths it causes is quite high at 6.9%. Cancer patients who use anthracycline-based chemotherapy experience loss of body weight, muscle, body cell mass, distribution of extracellular fluid expansion and reduced intracellular air. This study was to determine the change of the Body Mass index (BMI) and body composition of patients with locally advanced breast cancer (stage IIIA, IIIB and IIIC) who had undergone anthracycline-based chemotherapy.
Methods: This anthracycline-based observational analytical study of pre and post chemotherapy was conducted with a cross-sectional approach. Subjects were measured height by microtoise; weight, body composition, daily calorie intake (DCI) and basal metabolic rate (BMR) as measured by Bioelectrical Impendance Analysis (BIA).
Results: 47 locally advanced breast cancer patients underwent anthracycline-based chemotherapy. Based on the Wilcoxon statistical test, 6 variables with a 95% confidence level (p<0.05) showed a decrease in the value 5 variables, namely BMI, total body water (TBW), visceral fat, skeletal muscle mass and skeletal bone mass. Meanwhile, body fat showed a p value=0.224. The changes of variable confounding, DCI decrease (p=0.004), but BMR increase not significantly (p=0.795).
Conclusion: There is an effect of chemotherapy on nutritional status of BMI, TBW, visceral fat, skeletal muscle mass and bone mass in patients with locally advanced breast cancer who underwent anthracycline-based chemotherapy, which may the result of the calorie intake decreased, but not on body fat
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
This journal provides direct open access to its content on the principle that making research freely available to the public supports greater global knowledge exchange. IJCNP Journal offers all journal article writers to have their research openly available, free access and time-limited.
All articles published in Open Access will be immediately and permanently free for everyone, where the articles can be read and downloaded. With alicense CC BY-SA,
Authors retain copyright to their articles, but authors allow others to use the published content in whole or in part as long as the original work is cited properly. Users (redistributors) of IJCNP are asked to cite the original source, including the name of the author, IJCNP as the source of initial publication, year of publication, number and volume.
Copyright includes the exclusive right to reproduce and transmit this article in all forms and media, including reprints, photographs, microfilm and other similar reproductions, and translations thereof. Reproduction of any part of this journal, its database storage and transmission in any form or medium, such as electronic, electrostatic and mechanical copies, photocopying, recording, magnetic media.
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.